LPAL13_350058900

Calponin homology (CH) domain containing protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_129086 OG7: OG7_0006393 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340037400 ⚠
replication factor C, subunit 3, putative
— OG7
LPAL13_210023900 ⚠
pumillio protein 3, putative
— OG7
LPAL13_350005100 ⚠
PUF1, putative
— OG7
LPAL13_060005600 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LPAL13_180016800 ⚠
pumilio protein 2, putative
— OG7
LPAL13_170010500 ⚠
ATPase family associated with various cellula
— OG7
LPAL13_270012200 ⚠
replication factor C, subunit 4, putative
— OG7
LPAL13_200059300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_300030300 ⚠
replication factor C, subunit 2, putative
— OG7
LPAL13_200062500 ⚠
pumillio protein 9, putative
— OG7
LPAL13_200044100 ⚠
geranylgeranyltransferase, putative
— OG7
LPAL13_300013100 ⚠
heat shock protein grpe
— Both
LPAL13_230024100
Inositol hexakisphosphate, putative
— Both
LPAL13_150019200 ⚠
mismatch repair protein MSH3, putative
— Both
LPAL13_110012500
Leucine Rich repeat, putative
— Both
LPAL13_080009200
WD domain, G-beta repeat, putative
— Both
LPAL13_000018400
hypothetical protein, conserved
— Both
LPAL13_110012800
PUB domain containing protein, putative
— Both
LPAL13_330027100
Ribosome assembly protein rrb1, putative
— Both
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_060015300 ⚠
TLD, putative
— OG7
LPAL13_350026400 ⚠
TLD, putative
— OG7
LPAL13_340029100 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_200043400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_350053000 ⚠
ubiquitin protein ligase, putative
— OG7
LPAL13_350026300 ⚠
mismatch repair protein MSH8, putative
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_330031500
glycosyl hydrolase-like protein
— Both
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_300013000 ⚠
co-chaperone GrpE, putative
— OG7
LPAL13_330017200 ⚠
pumilio protein 6, putative
— OG7
LPAL13_200062600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_090010600
leucine-rich repeat protein, putative
— Both
LPAL13_340032200
IQ calmodulin-binding motif containing protei
— Both
LPAL13_340020700
Concanavalin A-like lectin/glucanases superfa
— Both
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— Both
LPAL13_180016100
hypothetical protein, conserved
— Both
LPAL13_260016500
hypothetical protein, conserved
— Both
LPAL13_300011100
hypothetical protein, conserved
— Both
LPAL13_320016900 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LPAL13_120008800 ⚠
pumillio protein 4, putative
— Both
LPAL13_030008900 ⚠
TLD domain protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.