LPAL13_270033900

Heat shock protein 100 kDa
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100223 OG7: OG7_0002479 179 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 179 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_250023800 ⚠
elongation factor 2-like protein
— Both
LPAL13_220012700 ⚠
Galactose oxidase, central domain/Kelch motif
— Both
LPAL13_300029300 ⚠
hypothetical protein
— Both
LPAL13_300028600 ⚠
Hsp70 protein, putative
— Both
LPAL13_300028700 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— Both
LPAL13_350006800 ⚠
elongation factor 2
— OG7
LPAL13_350020800 ⚠
Kelch motif containing protein, putative
— OG7
LPAL13_000010700 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LPAL13_280023500 ⚠
Galactose oxidase, central domain containing
— OG7
LPAL13_280029100 ⚠
Galactose oxidase, central domain containing
— OG7
LPAL13_300028800 ⚠
Hsp70 protein, putative
— Both
LPAL13_200051000 ⚠
kelch domain-containing protein
— OG7
LPAL13_240010400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LPAL13_350071800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_240027900 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LPAL13_300028500 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_260005100 ⚠
Lsm7p protein, putative
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— OG7
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_000037800 ⚠
hypothetical protein
— OG7
LPAL13_300026600 ⚠
Leucine rich repeat, putative
— OG7
LPAL13_330007100 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LPAL13_350053000 ⚠
ubiquitin protein ligase, putative
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_260012000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_000024500 ⚠
hydrogenase, putative
— Both
LPAL13_240006100 ⚠
ankyrin/TPR repeat protein
— OG6
LPAL13_140019200 ⚠
inositol-3-phosphate synthase
— Both
LPAL13_270016400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— Both
LPAL13_230018400 ⚠
hypothetical protein, conserved
— Both
LPAL13_210011600 ⚠
nucleotide-binding protein, putative
— Both
LPAL13_280032700 ⚠
MRP protein-like protein
— OG6
LPAL13_260009100 ⚠
nucleotide binding protein-like protein
— Both
LPAL13_000024800 ⚠
Ankyrin repeat, putative
— Both
LPAL13_000014700 ⚠
casein kinase II, alpha chain, putative
— OG6
LPAL13_280025800 ⚠
replication factor A, 51kDa subunit, putative
— Both
LPAL13_220013700 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_220013600 ⚠
Beta-lactamase superfamily domain containing
— Both
LPAL13_230008700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350049800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_050010300 ⚠
Translation initiation factor SUI1, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.