LPAL13_320022300

phosphomannose isomerase
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102059 OG7: OG7_0006704 159 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 159 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_060010700 ⚠
U-box domain containing protein, putative
— OG7
LPAL13_300012200
Phosphoinositide-specific phospholipase C, ef
— Both
LPAL13_310010500
amino acid transporter aATP11, putative
— OG6
LPAL13_260008000 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LPAL13_300029900 ⚠
formate--tetrahydrofolate ligase
— OG6
LPAL13_220006200
glutamine amidotransferase, putative
— Both
LPAL13_160011300
transaldolase, putative
— Both
LPAL13_350024400 ⚠
exoribonuclease 2, putative
— Both
LPAL13_060007900 ⚠
5'-3' exonuclease, putative
— Both
LPAL13_340029800
hypothetical protein, conserved
— Both
LPAL13_320031400
hypothetical protein, conserved
— Both
LPAL13_250016400 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
LPAL13_300030000
RNA-binding protein, putative
— OG6
LPAL13_280020600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LPAL13_340013000 ⚠
aspartate aminotransferase, putative
— Both
LPAL13_240008900 ⚠
aspartate aminotransferase, putative
— Both
LPAL13_000041700 ⚠
hypothetical protein
— Both
LPAL13_320027500 ⚠
Cytidylyltransferase, putative
— Both
LPAL13_280017700
WD domain, G-beta repeat, putative
— Both
LPAL13_180007800 ⚠
Dephospho-CoA kinase, putative
— Both
LPAL13_280018000
electron-transfer-flavoprotein, alpha polypep
— Both
LPAL13_230025700
alanine racemase, putative
— Both
LPAL13_220008200
SEP domain containing protein, putative
— Both
LPAL13_200027700
protein phosphatase 2C-like protein
— OG6
LPAL13_200041400
phosphomannomutase-like protein
— Both
LPAL13_280028200
tRNA threonylcarbamoyl adenosine modification
— Both
LPAL13_310006400
ubiquitin hydrolase, putative
— Both
LPAL13_010006600
cyclophilin 12, putative
— OG6
LPAL13_330037300 ⚠
transcription elongation factor-like protein
— Both
LPAL13_130019500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_000031000 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_310007900 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LPAL13_130006500 ⚠
MCAK-like kinesin, putative
— OG7
LPAL13_000034100
hypothetical protein, conserved
— OG7
LPAL13_310035400 ⚠
aldehyde reductase, putative
— OG7
LPAL13_270032500 ⚠
aldo-keto reductase-like protein
— OG7
LPAL13_220014200
ChaC-like protein, putative
— OG7
LPAL13_070005500 ⚠
alpha-adaptin-like protein
— OG7
LPAL13_200043500 ⚠
adaptor gamma-1 chain, putative
— OG7
LPAL13_000053700 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_280020800 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LPAL13_250016600 ⚠
dehydrogenase-like protein
— OG7
LPAL13_290007600 ⚠
thymine-7-hydroxylase, putative
— OG7
LPAL13_190020800 ⚠
eukaryotic translation initiation factor-like
— OG7
LPAL13_290022600 ⚠
serine/threonine protein kinase, putative
— OG7
LPAL13_210006600 ⚠
serine/threonine-protein kinase-like protein
— OG7
LPAL13_210005200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280020500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LPAL13_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.