LTRL590_070006100

metallo-peptidase, Clan ME, Family M16C
Leishmania tropica L590 OG6: OG6_101809 OG7: OG7_0004979 160 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 160 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_210017000 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LTRL590_340040900 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LTRL590_340018100 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LTRL590_180007500
RNA-binding protein 29, putative
— Both
LTRL590_360030300 ⚠
developmentally regulated GTP-binding protein
— Both
LTRL590_360031600
tyrosine aminotransferase
— Both
LTRL590_020008600
casein kinase II, alpha chain, putative
— OG6
LTRL590_130011800 ⚠
U-box domain containing protein, putative
— Both
LTRL590_130010500 ⚠
U-box domain containing protein, putative
— Both
LTRL590_050007200
hydrogenase, putative
— Both
LTRL590_350019800 ⚠
choline/ethanolamine kinase, putative
— Both
LTRL590_230012300 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LTRL590_360076300 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LTRL590_350036700
hypothetical protein, conserved
— Both
LTRL590_290018000 ⚠
Ankyrin repeats (3 copies), putative
— Both
LTRL590_030012900
TatD related DNase, putative
— Both
LTRL590_170019700
otubain cysteine peptidase, Clan CA, family C
— Both
LTRL590_280009400 ⚠
DIS3-like exonuclease, putative
— OG7
LTRL590_040008100 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LTRL590_180018400 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LTRL590_270020700 ⚠
choline kinase
— OG7
LTRL590_350060300 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LTRL590_130012900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LTRL590_210008900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LTRL590_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LTRL590_350059100 ⚠
GTP-binding protein, putative
— OG7
LTRL590_350028800 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LTRL590_050009100 ⚠
GTPase, putative
— OG7
LTRL590_330032400 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_360067400 ⚠
aminopeptidase P1, putative
— OG7
LTRL590_350019100 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LTRL590_170007900 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LTRL590_150018900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_160009300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LTRL590_090018800 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LTRL590_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LTRL590_300028600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_330007200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_120005700 ⚠
ribonuclease mar1
— OG7
LTRL590_110009900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_100006400 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LTRL590_270032400 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_360034600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LTRL590_290008000 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LTRL590_360051400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_100013100 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.