LTRL590_100012200

Eukaryotic translation initiation factor 4 gamma type 5, putative
Leishmania tropica L590 OG6: OG6_139892 OG7: OG7_0037732 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_320020300
G5-interacting protein, putative
— Both
LTRL590_230005500 ⚠
cyclophilin 11, putative
— OG6
LTRL590_170007200
histone H2A, putative
— OG7
LTRL590_310021300 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LTRL590_000016100 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LTRL590_120008800
CCR4-NOT transcription complex subunit 2, put
— Both
LTRL590_110011900
mRNA cap guanine-N7 methyltransferase, putati
— Both
LTRL590_210014100
Domain of unknown function (DUF3819)/CCR4-Not
— Both
LTRL590_360083300
Ribosomal protein L1p/L10e family, putative
— Both
LTRL590_010009300 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LTRL590_260007000
Eukaryotic translation initiation factor 4E t
— Both
LTRL590_060006700
hypothetical protein, conserved
— Both
LTRL590_040008300
hypothetical protein, conserved
— Both
LTRL590_090018400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250015300 ⚠
cyclophilin a
— OG6
LTRL590_330023900 ⚠
cyclophilin 4, putative
— OG6
LTRL590_090015200
hypothetical protein, conserved
— Both
LTRL590_080013200
Beta-lactamase superfamily domain containing
— Both
LTRL590_090018500 ⚠
hypothetical protein, conserved
— Both
LTRL590_020010200 ⚠
voltage-dependent anion-selective channel, pu
— Both
LTRL590_070011600
hypothetical protein, conserved
— Both
LTRL590_080006100
hypothetical protein, conserved
— Both
LTRL590_280013700 ⚠
RNA binding protein rbp16, putative
— Both
LTRL590_040005300
cAMP-specific phosphodiesterase, putative
— Both
LTRL590_040010600
DENN (AEX-3) domain containing protein, putat
— Both
LTRL590_110006500 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LTRL590_340037800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LTRL590_190011100 ⚠
histone H3 variant, putative
— OG7
LTRL590_170006700 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_290018200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_000021600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_210009500 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LTRL590_360084500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_300018300 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_330038900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360023100 ⚠
universal minicircle sequence binding protein
— OG6
LTRL590_350056900 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_240011900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_210014300 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LTRL590_350014600 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LTRL590_360056800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_330038800 ⚠
hypothetical protein
— OG7
LTRL590_320013300 ⚠
cyclin 9, putative
— OG7
LTRL590_320022300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_020010100 ⚠
voltage-dependent anion-selective channel, pu
— OG7
LTRL590_350054300 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LTRL590_160012800 ⚠
ubiquitin hydrolase, putative
— Both
LTRL590_320005100
nuclear segregation protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.