LTRL590_340046700

ubiquitin hydrolase, putative
Leishmania tropica L590 OG6: OG6_173868 OG7: OG7_0002166 238 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 238 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_040005300 ⚠
cAMP-specific phosphodiesterase, putative
— Both
LTRL590_330009000 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LTRL590_350036600 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LTRL590_230013900 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LTRL590_190012800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LTRL590_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LTRL590_360033100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210016800 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LTRL590_350039700 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LTRL590_360054700 ⚠
ubiquitin protein ligase, putative
— OG7
LTRL590_170008700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210009500 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LTRL590_330038400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360068300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_240015700 ⚠
replication factor C, subunit 1, putative
— OG7
LTRL590_360080800 ⚠
replication factor C, subunit 5, putative
— OG7
LTRL590_190011300 ⚠
Suppressor-of-White-APricot splicing regulato
— OG7
LTRL590_300018300 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_280034900 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LTRL590_260021600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_130015500 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
LTRL590_250019800 ⚠
RNA-binding protein RBP10, putative
— OG7
LTRL590_330038700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360069500 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG7
LTRL590_290021700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300035500 ⚠
protein mkt1, putative
— OG7
LTRL590_000028000 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LTRL590_320017400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_320005100 ⚠
nuclear segregation protein, putative
— OG7
LTRL590_210019200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_340008100 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_360015900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_160012800 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_180013600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_260012200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_310041000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_110010100 ⚠
chromatin binding protein, putative
— OG7
LTRL590_170006800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360051400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360034600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LTRL590_360040200 ⚠
fibrillarin
— OG7
LTRL590_320013300 ⚠
cyclin 9, putative
— OG7
LTRL590_190005600 ⚠
fibrillarin, putative
— OG7
LTRL590_280007300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_200016700 ⚠
MORN repeat-containing protein
— OG7
LTRL590_360074000 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.