LTRL590_130015500

DNA-directed RNA polymerase I subunit, putative
Leishmania tropica L590 OG6: OG6_101548 OG7: OG7_0007040 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_350039700 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LTRL590_360052300 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_190008900 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LTRL590_310026100 ⚠
hypothetical protein, conserved
— Both
LTRL590_330034100 ⚠
Unc104-like kinesin, putative
— OG6
LTRL590_280032500 ⚠
hypothetical protein, conserved
— Both
LTRL590_350021500 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LTRL590_300033600 ⚠
Stabilization of polarity axis, putative
— Both
LTRL590_300032500 ⚠
replication factor C, subunit 2, putative
— OG7
LTRL590_360068300 ⚠
hypothetical protein, conserved
— Both
LTRL590_260021600 ⚠
hypothetical protein, conserved
— Both
LTRL590_360069500 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
LTRL590_290021700 ⚠
hypothetical protein, conserved
— Both
LTRL590_340022500 ⚠
kinesin, putative
— OG6
LTRL590_300030200 ⚠
hypothetical protein, conserved
— Both
LTRL590_360032900 ⚠
hypothetical protein, conserved
— Both
LTRL590_350027200 ⚠
hypothetical protein, conserved
— Both
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
LTRL590_360080800 ⚠
replication factor C, subunit 5, putative
— OG7
LTRL590_240015700 ⚠
replication factor C, subunit 1, putative
— OG7
LTRL590_340025100 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_320013300 ⚠
cyclin 9, putative
— OG7
LTRL590_250012100 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LTRL590_190011400 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LTRL590_180013300 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LTRL590_340037800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LTRL590_090017500 ⚠
SHS2 domain found in N terminus of Rpb7p/Rpc2
— OG7
LTRL590_090017600 ⚠
hypothetical protein
— OG7
LTRL590_090017200 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
LTRL590_080013200 ⚠
Beta-lactamase superfamily domain containing
— Both
LTRL590_320019300 ⚠
RNA polymerase-like protein, putative
— Both
LTRL590_200016700 ⚠
MORN repeat-containing protein
— Both
LTRL590_280028100 ⚠
DNA-directed RNA polymerase-like protein
— Both
LTRL590_280006200 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— Both
LTRL590_180013200 ⚠
DNA-directed RNA polymerase II/III subunit, p
— Both
LTRL590_250007000 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LTRL590_090022500 ⚠
hypothetical protein, conserved
— Both
LTRL590_190011300 ⚠
Suppressor-of-White-APricot splicing regulato
— Both
LTRL590_080006100 ⚠
hypothetical protein, conserved
— Both
LTRL590_280013400 ⚠
RNA polymerase B subunit RPB8, putative
— Both
LTRL590_150018900 ⚠
ubiquitin hydrolase, putative
— Both
LTRL590_210019200 ⚠
hypothetical protein, conserved
— Both
LTRL590_200016600 ⚠
hypothetical protein, conserved
— Both
LTRL590_200010900 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— Both
LTRL590_000024100 ⚠
hypothetical protein, conserved
— Both
LTRL590_110005600 ⚠
protein kinase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.