LTRL590_250012100

RNA polymerase I second largest subunit, putative
Leishmania tropica L590 OG6: OG6_102249 OG7: OG7_0001821 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_310039100 ⚠
RNA polymerase ii largest subunit
— +1 more OG7
LTRL590_040006400 ⚠
exosome complex exonuclease RRP40, putative
— Both
LTRL590_000028500 ⚠
RNA polymerase ii largest subunit
— +1 more OG7
LTRL590_310039200 ⚠
RNA polymerase ii largest subunit
— +1 more OG7
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LTRL590_160020500 ⚠
DNA-directed rna polymerase I largest subunit
— +3 more Both
LTRL590_340008800 ⚠
RNA polymerase ii largest subunit
— +1 more OG7
LTRL590_290006600 ⚠
DNA-directed RNA polymerase I-like protein
— OG7
LTRL590_190011400 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LTRL590_310039500 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LTRL590_280028100 ⚠
DNA-directed RNA polymerase-like protein
— OG7
LTRL590_270021900 ⚠
DNA-directed RNA polymerase II-like protein
— OG7
LTRL590_310039600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LTRL590_230025200 ⚠
Csl4p homologue, putative
— Both
LTRL590_290025000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LTRL590_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LTRL590_170014500 ⚠
formin, putative
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LTRL590_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_140020300 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LTRL590_350041200 ⚠
zinc finger protein, putative
— OG7
LTRL590_020006000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LTRL590_360032400 ⚠
Cullin protein neddylation domain containing
— OG7
LTRL590_360081400 ⚠
beta-adaptin, putative
— OG7
LTRL590_240030500 ⚠
cullin-like protein-like protein
— OG7
LTRL590_190013800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350049500 ⚠
predicted zinc finger protein
— OG7
LTRL590_050008100 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LTRL590_090007300 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LTRL590_260005500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_160019300 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— Both
LTRL590_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LTRL590_280013400 ⚠
RNA polymerase B subunit RPB8, putative
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_090014500 ⚠
ubiquitin-fusion protein
— OG7
LTRL590_060010200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_360067800 ⚠
beta-adaptin protein, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_240024100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_180011300 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LTRL590_360040100 ⚠
cullin-like protein
— OG7
LTRL590_310030400 ⚠
polyubiquitin, putative
— OG7
LTRL590_360060400 ⚠
exosome-associated protein 4, putative
— OG7
LTRL590_350055900 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LTRL590_360011700 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.