LTRL590_040006400

exosome complex exonuclease RRP40, putative
Leishmania tropica L590 OG6: OG6_102463 OG7: OG7_0007513 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_250012100 ⚠
RNA polymerase I second largest subunit, puta
— Both
LTRL590_020008200 ⚠
ribosomal RNA processing protein, putative
— Both
LTRL590_360039600 ⚠
exosome complex exonuclease RRP41, putative
— Both
LTRL590_360060400 ⚠
exosome-associated protein 4, putative
— OG7
LTRL590_200005000 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LTRL590_310006300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LTRL590_200019800
RNasePH-like protein
— Both
LTRL590_230025200
Csl4p homologue, putative
— Both
LTRL590_320043200 ⚠
exosome-associated protein 2, putative
— +2 more Both
LTRL590_220020400 ⚠
exosome complex exonuclease RRP45 homolog, pu
— +2 more Both
LTRL590_140005000
exosome complex exonuclease, putative
— Both
LTRL590_280035700 ⚠
heat-shock protein hsp70, putative
— OG6
LTRL590_010011800 ⚠
HSP70-like protein
— OG7
LTRL590_260017200 ⚠
heat-shock protein hsp70, putative
— Both
LTRL590_250019300
hypothetical protein, conserved
— Both
LTRL590_250020700 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LTRL590_030008300
protein kinase, putative
— Both
LTRL590_340013800 ⚠
elongation factor 1-beta
— Both
LTRL590_360020700 ⚠
translation elongation factor 1-beta, putativ
— Both
LTRL590_260009400 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LTRL590_260009500 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_060010200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_090014500 ⚠
ubiquitin-fusion protein
— OG7
LTRL590_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LTRL590_360067800 ⚠
beta-adaptin protein, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350041300 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LTRL590_240024100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_160019300 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_300028600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_280031400 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LTRL590_040014500 ⚠
adenylate kinase, putative
— OG7
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LTRL590_330035700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_360050700 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LTRL590_180011300 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LTRL590_360024000 ⚠
neurobeachin/beige protein, putative
— OG7
LTRL590_360011700 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_350055900 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LTRL590_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LTRL590_190008900 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LTRL590_080014700 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LTRL590_310030400 ⚠
polyubiquitin, putative
— OG7
LTRL590_360040100 ⚠
cullin-like protein
— OG7
LTRL590_360019900 ⚠
adenylate kinase, putative
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.