LTRL590_280031400

DNA replication licensing factor MCM6, putative
Leishmania tropica L590 OG6: OG6_101983 OG7: OG7_0001163 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_330035700 ⚠
DNA replication licensing factor MCM3, putati
— +18 more Both
LTRL590_280014100 ⚠
DNA replication licensing factor MCM2, putati
— +19 more Both
LTRL590_320037500 ⚠
DNA replication licensing factor MCM7, putati
— +19 more Both
LTRL590_090007300 ⚠
DNA replication licensing factor MCM4, putati
— +18 more Both
LTRL590_240014900 ⚠
DNA replication licensing factor MCM5, putati
— +18 more Both
LTRL590_050008100 ⚠
DNA replication licensing factor MCM8, putati
— +18 more Both
LTRL590_350055900 ⚠
DNA replication licensing factor MCM9, putati
— +17 more OG7
LTRL590_020006000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LTRL590_070011600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340045100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LTRL590_340023700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_140020300 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LTRL590_310019500 ⚠
Ubiquitin homologues, putative
— OG7
LTRL590_320034200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_300008000 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LTRL590_340024700 ⚠
ubiquitin-like protein
— OG7
LTRL590_070009600 ⚠
RAVE protein 1 C terminal, putative
— OG7
LTRL590_110007900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250015600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_300028600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_110009900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LTRL590_270032400 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LTRL590_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_290008000 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LTRL590_200013600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LTRL590_220021000 ⚠
CCR4 associated factor, putative
— OG7
LTRL590_160019300 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_250019400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_310039100 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_110010600 ⚠
pumillio protein 10, putative
— OG7
LTRL590_250022000 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LTRL590_260010800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_040006400 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LTRL590_140011800 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_090014900 ⚠
SLA/LP autoantigen-like protein
— OG7
LTRL590_310025200 ⚠
GINS complex subunit Psf3, putative
— OG7
LTRL590_110009600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_160012100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_180011000 ⚠
Flagellar-associated PapD-like, putative
— OG7
LTRL590_180013700 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LTRL590_340008800 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_240028500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250019600 ⚠
PRP38 family, putative
— OG7
LTRL590_360032400 ⚠
Cullin protein neddylation domain containing
— OG7
LTRL590_160020500 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.