LTRL590_220021000

CCR4 associated factor, putative
Leishmania tropica L590 OG6: OG6_101138 OG7: OG7_0005422 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_210014100
Domain of unknown function (DUF3819)/CCR4-Not
— Both
LTRL590_250025600
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LTRL590_120008800
CCR4-NOT transcription complex subunit 2, put
— Both
LTRL590_340049700
cell differentiation protein-like protein
— Both
LTRL590_230005100
hypothetical protein, conserved
— Both
LTRL590_090014500 ⚠
ubiquitin-fusion protein
— OG7
LTRL590_200016900 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LTRL590_270006600
zinc finger containing protein, putative
— OG6
LTRL590_360073500
CCR4-NOT transcription complex subunit 10, pu
— Both
LTRL590_190011700 ⚠
kinesin, putative
— OG6
LTRL590_160020500 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LTRL590_190011600 ⚠
kinesin, putative
— OG6
LTRL590_150014000
hypothetical protein, conserved
— Both
LTRL590_220020500
hypothetical protein, conserved
— Both
LTRL590_140011800
WD domain, G-beta repeat, putative
— Both
LTRL590_120011700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LTRL590_300027700
RNA-binding protein, putative
— OG6
LTRL590_060017200
hypothetical protein, conserved
— Both
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— Both
LTRL590_090018900
AAA family ATPase, putative
— Both
LTRL590_050015500 ⚠
MORN repeat, putative
— OG7
LTRL590_340029800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LTRL590_340028700 ⚠
Sec7 domain containing protein, putative
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_160018500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_000005800 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LTRL590_300028600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_110009900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LTRL590_270032400 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LTRL590_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_290008000 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LTRL590_200013600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LTRL590_300036400
zinc finger containing protein, putative
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_360038600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_130019400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_200005000 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LTRL590_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LTRL590_360032400 ⚠
Cullin protein neddylation domain containing
— OG7
LTRL590_020006000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.