LTRL590_130019400

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania tropica L590 OG6: OG6_158186 OG7: OG7_0009410 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_340045100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LTRL590_350041300 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LTRL590_330008300 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_060007600 ⚠
5'-3' exonuclease, putative
— OG7
LTRL590_360024700 ⚠
exoribonuclease 2, putative
— OG7
LTRL590_170016700 ⚠
5'-3' exonuclease, putative
— OG7
LTRL590_030007500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_030007600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_120006500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_020006000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LTRL590_200016900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LTRL590_210021300 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LTRL590_190005600 ⚠
fibrillarin, putative
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_360038600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LTRL590_360040200 ⚠
fibrillarin
— OG7
LTRL590_330012400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330018100 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LTRL590_210017700 ⚠
dynein arm light chain, putative
— OG7
LTRL590_240014200 ⚠
dynein arm light chain, putative
— OG7
LTRL590_260016000 ⚠
Axonemal dynein light chain, putative
— OG7
LTRL590_130006500 ⚠
protein kinase A regulatory subunit, putative
— OG7
LTRL590_320007600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250025600 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG7
LTRL590_060017200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210014100 ⚠
Domain of unknown function (DUF3819)/CCR4-Not
— OG7
LTRL590_320020000 ⚠
cleavage and polyadenylation specificity fact
— OG7
LTRL590_040010400 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LTRL590_140014300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_200007800 ⚠
Midasin, putative
— OG7
LTRL590_190014200 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_110015400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210011000 ⚠
Tetratricopeptide repeat, putative
— OG7
LTRL590_360016100 ⚠
intraflagellar transport protein IFT122, puta
— OG7
LTRL590_320047900 ⚠
cAMP response protein, putative
— OG7
LTRL590_150017400 ⚠
protein kinase, putative
— OG7
LTRL590_340033300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LTRL590_290018800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300005600 ⚠
MATH domain containing protein, putative
— OG7
LTRL590_300012400 ⚠
Phosphatidylinositol-specific phospholipase C
— OG7
LTRL590_240027300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_230005100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_050008700 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LTRL590_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LTRL590_050015500 ⚠
MORN repeat, putative
— OG7
LTRL590_230017900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_160018500 ⚠
WW domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.