LTRL590_040010400

Tetratricopeptide repeat/TPR repeat, putative
Leishmania tropica L590 OG6: OG6_102882 OG7: OG7_0007593 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_270017900 ⚠
translation initiation factor eIF2B subunit-l
— OG7
LTRL590_240027400
hypothetical protein, conserved
— Both
LTRL590_090013500
kinetoplast-associated protein-like protein
— OG6
LTRL590_360034900
protein kinase, putative
— Both
LTRL590_140014300
hypothetical protein, conserved
— Both
LTRL590_360076000 ⚠
ubiquitin-protein ligase, putative
— Both
LTRL590_260024500 ⚠
microtubule-associated protein, putative
— Both
LTRL590_240027300
hypothetical protein, conserved
— Both
LTRL590_210021300 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— Both
LTRL590_120011700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LTRL590_110015400
hypothetical protein, conserved
— Both
LTRL590_090018900
AAA family ATPase, putative
— Both
LTRL590_050006800
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— Both
LTRL590_340022300
hypothetical protein, conserved
— Both
LTRL590_270029000 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_180016300 ⚠
protein kinase A catalytic subunit
— OG6
LTRL590_280031400 ⚠
DNA replication licensing factor MCM6, putati
— Both
LTRL590_020006000 ⚠
phosphatidylinositol kinase related protein,
— Both
LTRL590_030015300 ⚠
MORN repeat, putative
— Both
LTRL590_110020200
hypothetical protein, conserved
— Both
LTRL590_050015500 ⚠
MORN repeat, putative
— OG7
LTRL590_360038600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_340045100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LTRL590_130019400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_340033300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LTRL590_330040200 ⚠
46 kD virulence factor
— OG7
LTRL590_340021000 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LTRL590_340048900 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LTRL590_170016700 ⚠
5'-3' exonuclease, putative
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_340023300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_160023200 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_350041300 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LTRL590_290018000 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LTRL590_210024200 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LTRL590_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LTRL590_340028700 ⚠
Sec7 domain containing protein, putative
— OG7
LTRL590_200018300 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LTRL590_240014200 ⚠
dynein arm light chain, putative
— OG7
LTRL590_210017700 ⚠
dynein arm light chain, putative
— OG7
LTRL590_100010900 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_330018100 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LTRL590_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LTRL590_300037600 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LTRL590_090015300 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LTRL590_050008100 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LTRL590_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.