LTRL590_360075700

target of rapamycin (TOR) kinase 1, putative
Leishmania tropica L590 OG6: OG6_100794 OG7: OG7_0001934 341 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 341 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LTRL590_310039600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_310039500 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_290025000 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LTRL590_320036300 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— OG7
LTRL590_360064100 ⚠
glycosyl hydrolase, putative
— OG7
LTRL590_330022300 ⚠
Tetratricopeptide repeats, putative
— Both
LTRL590_320020200 ⚠
RNA guanylyltransferase, putative
— OG7
LTRL590_190006200 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LTRL590_160005200 ⚠
AAA domain containing protein, putative
— OG7
LTRL590_360019900 ⚠
adenylate kinase, putative
— OG7
LTRL590_210020400 ⚠
adenylate kinase, putative
— OG7
LTRL590_180013700 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LTRL590_040014500 ⚠
adenylate kinase, putative
— OG7
LTRL590_040013800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_320020600 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LTRL590_130008900 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_170014400 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LTRL590_170018800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340008800 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_310039100 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_000028500 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_310039200 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_360024000 ⚠
neurobeachin/beige protein, putative
— OG7
LTRL590_160020500 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LTRL590_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_080009600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_150014000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_240028500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_040009900 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LTRL590_260009600 ⚠
DNA polymerase sigma-like protein
— OG7
LTRL590_070013200 ⚠
topoisomerase-related function protein-like p
— OG7
LTRL590_360050700 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LTRL590_320040100 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
LTRL590_250019600 ⚠
PRP38 family, putative
— OG7
LTRL590_170008700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_180009900 ⚠
tubulin-specific chaperone, putative
— OG7
LTRL590_360032400 ⚠
Cullin protein neddylation domain containing
— OG7
LTRL590_240030500 ⚠
cullin-like protein-like protein
— OG7
LTRL590_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_360040100 ⚠
cullin-like protein
— OG7
LTRL590_250019400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_160019300 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_220021000 ⚠
CCR4 associated factor, putative
— OG7
LTRL590_360011700 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_140020300 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LTRL590_310030400 ⚠
polyubiquitin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.