LTRL590_170014400

ATP-dependent RNA helicase, putative
Leishmania tropica L590 OG6: OG6_100305 OG7: OG7_0001850 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_350046100 ⚠
U5 snRNA-associated splicing factor
— Both
LTRL590_310043700 ⚠
Carbamoyl-phosphate synthase L chain, N-termi
— Both
LTRL590_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_250019400 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LTRL590_360032400 ⚠
Cullin protein neddylation domain containing
— OG7
LTRL590_240030500 ⚠
cullin-like protein-like protein
— OG7
LTRL590_310043600 ⚠
acetyl-CoA carboxylase, putative
— Both
LTRL590_160019300 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LTRL590_360040100 ⚠
cullin-like protein
— OG7
LTRL590_140011800 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_310019500 ⚠
Ubiquitin homologues, putative
— Both
LTRL590_330017300 ⚠
hypothetical protein, conserved
— Both
LTRL590_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LTRL590_180013700 ⚠
Periodic tryptophan protein 2 homolog, putati
— Both
LTRL590_180013600 ⚠
hypothetical protein, conserved
— Both
LTRL590_200013400 ⚠
protein kinase, putative
— OG6
LTRL590_150017300 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LTRL590_020008700 ⚠
proteasome regulatory non-ATPase subunit 6, p
— Both
LTRL590_130015200 ⚠
proteasome regulatory ATPase subunit 2, putat
— OG6
LTRL590_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LTRL590_270021100 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— Both
LTRL590_080010500 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LTRL590_320029300 ⚠
small nuclear ribonucleoprotein component-lik
— Both
LTRL590_360054600 ⚠
proteasome regulatory ATPase subunit
— OG6
LTRL590_330008300 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_320028400 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LTRL590_320047500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LTRL590_080014700 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LTRL590_330026700 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LTRL590_360065700 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LTRL590_340050400 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_060010200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_070008400 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LTRL590_360067800 ⚠
beta-adaptin protein, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_240024100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_040014500 ⚠
adenylate kinase, putative
— OG7
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_210021300 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_310039100 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_000028500 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_160005200 ⚠
AAA domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.