LTRL590_250019400

Cullin family/Cullin protein neddylation domain containing protein, putative
Leishmania tropica L590 OG6: OG6_168578 OG7: OG7_0001577 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_320020600 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LTRL590_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LTRL590_170014400 ⚠
ATP-dependent RNA helicase, putative
— Both
LTRL590_130008900 ⚠
ATP-dependent RNA helicase, putative
— Both
LTRL590_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LTRL590_240028500 ⚠
hypothetical protein, conserved
— Both
LTRL590_150012500 ⚠
hypothetical protein, conserved
— Both
LTRL590_180013600 ⚠
hypothetical protein, conserved
— Both
LTRL590_080010500 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LTRL590_230025200 ⚠
Csl4p homologue, putative
— Both
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— Both
LTRL590_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LTRL590_280025700 ⚠
AARP2CN (NUC121) domain/Protein of unknown fu
— OG7
LTRL590_200005000 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LTRL590_310006300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LTRL590_170014500 ⚠
formin, putative
— OG7
LTRL590_080014700 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LTRL590_330026700 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LTRL590_360065700 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LTRL590_300028600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_110009900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LTRL590_270032400 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LTRL590_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_290008000 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LTRL590_200013600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_060010200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_090014500 ⚠
ubiquitin-fusion protein
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_360067800 ⚠
beta-adaptin protein, putative
— OG7
LTRL590_240024100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_280031400 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LTRL590_330035700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LTRL590_180011300 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LTRL590_040014500 ⚠
adenylate kinase, putative
— OG7
LTRL590_360024000 ⚠
neurobeachin/beige protein, putative
— OG7
LTRL590_310039200 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_000028500 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_310039100 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_340008800 ⚠
RNA polymerase ii largest subunit
— OG7
LTRL590_330042100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_050008700 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LTRL590_350041300 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.