LTRL590_330008300

WD domain, G-beta repeat, putative
Leishmania tropica L590 OG6: OG6_103995 OG7: OG7_0008721 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_320028400
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LTRL590_220010700
proteasome regulatory ATPase subunit 1, putat
— OG6
LTRL590_340029800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LTRL590_290016600
kinesin, putative
— OG6
LTRL590_260024900 ⚠
microtubule-associated protein, putative
— Both
LTRL590_260024500 ⚠
microtubule-associated protein, putative
— Both
LTRL590_320008200
hypothetical protein, conserved
— Both
LTRL590_270021100
proteasome regulatory non-ATP-ase subunit 3,
— Both
LTRL590_220019500 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LTRL590_220019400 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LTRL590_360054600
proteasome regulatory ATPase subunit
— OG6
LTRL590_290006400
proteasome regulatory non-ATPase subunit, put
— Both
LTRL590_170014400 ⚠
ATP-dependent RNA helicase, putative
— Both
LTRL590_150017300 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LTRL590_120007400
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LTRL590_170013000
OSM3-like kinesin, putative
— OG6
LTRL590_070019400
proteasome regulatory non-ATP-ase subunit, pu
— Both
LTRL590_320009000
19S proteasome non-atpase subunit 8
— Both
LTRL590_190015400
proteasome regulatory non-ATP-ase subunit 9,
— Both
LTRL590_130008900 ⚠
ATP-dependent RNA helicase, putative
— Both
LTRL590_210013700
proteasome regulatory non-ATP-ase subunit 5,
— Both
LTRL590_320047500
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LTRL590_120005100 ⚠
translation initiation factor EIF-2b alpha su
— Both
LTRL590_090018900
AAA family ATPase, putative
— Both
LTRL590_160023200 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_270017900 ⚠
translation initiation factor eIF2B subunit-l
— OG7
LTRL590_100010900 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LTRL590_330040200 ⚠
46 kD virulence factor
— OG7
LTRL590_330040300 ⚠
46 kD virulence factor
— OG7
LTRL590_330018100 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LTRL590_320012300
OSM3-like kinesin, putative
— OG6
LTRL590_320047900 ⚠
cAMP response protein, putative
— OG7
LTRL590_340033300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LTRL590_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LTRL590_350041300 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LTRL590_130019400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_170016700 ⚠
5'-3' exonuclease, putative
— OG7
LTRL590_030007500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_030007600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_200016900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LTRL590_340045100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LTRL590_320021200 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LTRL590_360038600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_160018500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_210024200 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LTRL590_340028700 ⚠
Sec7 domain containing protein, putative
— OG7
LTRL590_130006500 ⚠
protein kinase A regulatory subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.