LTRL590_220019500

ATP-dependent DEAD/H RNA helicase, putative
Leishmania tropica L590 OG6: OG6_126543 OG7: OG7_0000698 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_360015900 ⚠
hypothetical protein, conserved
— OG6
LTRL590_330038400 ⚠
hypothetical protein, conserved
— OG6
LTRL590_360068300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_330008300 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_280034900 ⚠
Uncharacterized ACR, COG1678, putative
— OG6
LTRL590_250025600 ⚠
Not1 N-terminal domain, CCR4-Not complex comp
— OG6
LTRL590_330022300 ⚠
Tetratricopeptide repeats, putative
— OG6
LTRL590_360069500 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG6
LTRL590_320021300 ⚠
Microtubule-binding protein MIP-T3, putative
— OG6
LTRL590_290034700 ⚠
serine/threonine-protein kinase Nek3, putativ
— OG6
LTRL590_300035500 ⚠
protein mkt1, putative
— OG6
LTRL590_340008100 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_350039000 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LTRL590_300030200 ⚠
hypothetical protein, conserved
— OG6
LTRL590_360074000 ⚠
hypothetical protein, conserved
— OG6
LTRL590_260024900 ⚠
microtubule-associated protein, putative
— OG6
LTRL590_320008200 ⚠
hypothetical protein, conserved
— OG6
LTRL590_230017900 ⚠
hypothetical protein, conserved
— OG6
LTRL590_290018800 ⚠
hypothetical protein, conserved
— OG6
LTRL590_340049500 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG6
LTRL590_350038900 ⚠
60S ribosomal subunit protein L31, putative
— OG6
LTRL590_350022500 ⚠
casein kinase II, putative
— OG6
LTRL590_300005600 ⚠
MATH domain containing protein, putative
— OG6
LTRL590_280007300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_330034100 ⚠
Unc104-like kinesin, putative
— OG6
LTRL590_090018900 ⚠
AAA family ATPase, putative
— OG6
LTRL590_120005100 ⚠
translation initiation factor EIF-2b alpha su
— OG6
LTRL590_010009300 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
LTRL590_150015600 ⚠
protein phosphatase 2A regulatory subunit, pu
— OG6
LTRL590_060006700 ⚠
hypothetical protein, conserved
— OG6
LTRL590_160012800 ⚠
ubiquitin hydrolase, putative
— OG6
LTRL590_180019700 ⚠
Protein of unknown function (DUF3648), putati
— OG6
LTRL590_220010700 ⚠
proteasome regulatory ATPase subunit 1, putat
— OG6
LTRL590_040008300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_270029000 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_340022300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_300010600 ⚠
hypothetical protein, conserved
— OG6
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG6
LTRL590_240027300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_260024500 ⚠
microtubule-associated protein, putative
— OG6
LTRL590_360076000 ⚠
ubiquitin-protein ligase, putative
— OG6
LTRL590_300033600 ⚠
Stabilization of polarity axis, putative
— OG6
LTRL590_360033100 ⚠
hypothetical protein, conserved
— OG6
LTRL590_350039700 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
LTRL590_260016000 ⚠
Axonemal dynein light chain, putative
— OG6
LTRL590_290019300 ⚠
COPII coat assembly protein sec16, putative
— OG6
LTRL590_290016600 ⚠
kinesin, putative
— OG6
LTRL590_300011500 ⚠
AMP-binding enzyme, putative
— OG6
LTRL590_060007600 ⚠
5'-3' exonuclease, putative
— OG6
LTRL590_360024700 ⚠
exoribonuclease 2, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.