LTRL590_340029800

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain/Domain of unknown function (DUF1981), putative
Leishmania tropica L590 OG6: OG6_154458 OG7: OG7_0001170 177 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 177 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_040011900 ⚠
Axonemal dynein light chain, putative
— OG7
LTRL590_330008300 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_300027900 ⚠
endosomal trafficking protein RME-8, putative
— OG7
LTRL590_330025600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170008700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340019200 ⚠
inositol 5-phosphatase-like protein
— OG7
LTRL590_120010600 ⚠
WW domain containing protein, putative
— OG7
LTRL590_340045100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LTRL590_360083800 ⚠
elks delta-like protein
— OG7
LTRL590_360059700 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_360016100 ⚠
intraflagellar transport protein IFT122, puta
— OG7
LTRL590_260016000 ⚠
Axonemal dynein light chain, putative
— OG7
LTRL590_240014200 ⚠
dynein arm light chain, putative
— OG7
LTRL590_210017700 ⚠
dynein arm light chain, putative
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_240014000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LTRL590_150017700 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LTRL590_140014300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_100010900 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LTRL590_280031500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_140015200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_330018100 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LTRL590_360076000 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_240027300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210021300 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LTRL590_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LTRL590_260024500 ⚠
microtubule-associated protein, putative
— OG7
LTRL590_120011700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
LTRL590_310006000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_090018900 ⚠
AAA family ATPase, putative
— OG7
LTRL590_350049200 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LTRL590_110015400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360075700 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_350029200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350010900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340022300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350032500 ⚠
Transport protein Trs120 or TRAPPC9, TRAPP II
— OG7
LTRL590_270029000 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_150012500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_040012500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_040010200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250023200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250022800 ⚠
ER-Golgi trafficking TRAPP I complex 85 kDa s
— OG7
LTRL590_290006000 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_330035000 ⚠
dynein intermediate chain, putative
— OG7
LTRL590_240016400 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LTRL590_340014100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_240007800 ⚠
dynein intermediate-chain-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.