LTRL590_310043600

acetyl-CoA carboxylase, putative

Leishmania tropica L590 OG6: OG6_101052 OG7: OG7_0001434 199 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 199 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_080014700 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 Tb927.5.2960 ↔ Tb927.8.7100 OG6 TCSYLVIO_002772 ↔ TCSYLVIO_010787 OG7 LdBPK_080520.1 ↔ LdBPK_313080.1 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_010787 +5 more	Both
LTRL590_080010500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG6 Tb927.5.3170 ↔ Tb927.8.7100 OG6 LdBPK_080520.1 ↔ LdBPK_313080.1 OG7 LdBPK_080520.1 ↔ LdBPK_313080.1 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_010787 +5 more	Both
LTRL590_360065700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 Tb927.11.3030 ↔ Tb927.8.7100 OG6 Tb927.10.9430 ↔ Tb927.8.7100 OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004731 OG7 LdBPK_080520.1 ↔ LdBPK_313080.1 +6 more	Both
LTRL590_330026700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 Tb927.11.3030 ↔ Tb927.8.7100 OG6 Tb927.10.9430 ↔ Tb927.8.7100 OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004731 OG7 LdBPK_080520.1 ↔ LdBPK_313080.1 +6 more	Both
LTRL590_310039100 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.4.5020 ↔ Tb927.8.7100 OG7 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 Tb927.4.5020 ↔ Tb927.8.7100	Both
LTRL590_000028500 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.4.5020 ↔ Tb927.8.7100 OG7 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 Tb927.4.5020 ↔ Tb927.8.7100	Both
LTRL590_310039200 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.4.5020 ↔ Tb927.8.7100 OG7 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 Tb927.4.5020 ↔ Tb927.8.7100	Both
LTRL590_340008800 ⚠ RNA polymerase ii largest subunit	—	OG6 Tb927.4.5020 ↔ Tb927.8.7100 OG7 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 Tb927.4.5020 ↔ Tb927.8.7100	Both
LTRL590_320020600 ⚠ DEAD/DEAH box helicase-like protein, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 LdBPK_130390.1 ↔ LdBPK_313080.1	OG7
LTRL590_230023400 ⚠ DNA polymerase theta (helicase domain only),	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 LdBPK_130390.1 ↔ LdBPK_313080.1	OG7
LTRL590_160020500 ⚠ DNA-directed rna polymerase I largest subunit	—	OG6 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 LdBPK_161420.1 ↔ LdBPK_313080.1 OG7 Tb927.4.5020 ↔ Tb927.8.7100	Both
LTRL590_170014400 ⚠ ATP-dependent RNA helicase, putative	—	OG6 LdBPK_130390.1 ↔ LdBPK_313080.1 OG6 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 LdBPK_130390.1 ↔ LdBPK_313080.1	Both
LTRL590_130008900 ⚠ ATP-dependent RNA helicase, putative	—	OG6 LdBPK_130390.1 ↔ LdBPK_313080.1 OG6 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008995 OG7 LdBPK_130390.1 ↔ LdBPK_313080.1	Both
LTRL590_360023200 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_006999	OG7
LTRL590_190015400 ⚠ proteasome regulatory non-ATP-ase subunit 9,	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_005996 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005996	Both
LTRL590_360039400 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004479	OG7
LTRL590_130021800 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_002772	OG7
LTRL590_270007000 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_002772	OG7
LTRL590_360022700 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_002772	OG7
LTRL590_340050400 ⚠ Cyclic nucleotide-binding domain containing p	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_007057	OG7
LTRL590_210027500 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_002772	OG7
LTRL590_360083200 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008271	OG7
LTRL590_270018500 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008271	OG7
LTRL590_300015300 ⚠ ubiquitin-protein ligase, putative	—	OG7 LdBPK_301150.1 ↔ LdBPK_313080.1	OG7
LTRL590_160018500 ⚠ WW domain containing protein, putative	—	OG7 LdBPK_301150.1 ↔ LdBPK_313080.1	OG7
LTRL590_350061200 ⚠ SPRY domain/HECT-domain (ubiquitin-transferas	—	OG7 LdBPK_301150.1 ↔ LdBPK_313080.1	OG7
LTRL590_070008400 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_301150.1 ↔ LdBPK_313080.1	OG7
LTRL590_310006300 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 LdBPK_250630.1 ↔ LdBPK_313080.1	OG7
LTRL590_200005000 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 LdBPK_250630.1 ↔ LdBPK_313080.1	OG7
LTRL590_050009500 ⚠ ATPase alpha subunit	—	OG6 Tb927.7.7420 ↔ Tb927.8.7100 OG7 Tb927.7.7420 ↔ Tb927.8.7100	Both
LTRL590_300019100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_301340.1 ↔ LdBPK_313080.1 OG7 LdBPK_301340.1 ↔ LdBPK_313080.1	Both
LTRL590_230011800 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_230610.1 ↔ LdBPK_313080.1 OG7 LdBPK_230610.1 ↔ LdBPK_313080.1	Both
LTRL590_070019400 ⚠ proteasome regulatory non-ATP-ase subunit, pu	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009688	Both
LTRL590_330008300 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_005994 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005994	Both
LTRL590_210013700 ⚠ proteasome regulatory non-ATP-ase subunit 5,	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_007986 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_007986	Both
LTRL590_320018500 ⚠ proteasome regulatory non-ATP-ase subunit, pu	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004183 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004183	Both
LTRL590_010006900 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_003465 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_003465	Both
LTRL590_320036000 ⚠ proteasome regulatory non-ATP-ase subunit, pu	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_005383 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005383	Both
LTRL590_320028400 ⚠ RNA recognition motif. (a.k.a. RRM, RBD, or R	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004088 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004088	Both
LTRL590_340012200 ⚠ proteasome regulatory non-ATPase subunit 11,	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004531 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004531	Both
LTRL590_210026200 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_002772	Both
LTRL590_240016400 ⚠ AKAP7 2'5' RNA ligase-like domain containing	—	OG6 LdBPK_241080.1 ↔ LdBPK_313080.1 OG7 LdBPK_241080.1 ↔ LdBPK_313080.1	Both
LTRL590_140011800 ⚠ WD domain, G-beta repeat, putative	—	OG6 LdBPK_140580.1 ↔ LdBPK_313080.1 OG7 LdBPK_140580.1 ↔ LdBPK_313080.1	Both
LTRL590_300017100 ⚠ WW domain containing protein, putative	—	OG6 LdBPK_301150.1 ↔ LdBPK_313080.1 OG7 LdBPK_301150.1 ↔ LdBPK_313080.1	Both
LTRL590_310019400 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_311230.1 ↔ LdBPK_313080.1 OG7 LdBPK_311230.1 ↔ LdBPK_313080.1	Both
LTRL590_270013800 ⚠ parallel beta-helix repeat, putative	—	OG6 LdBPK_270680.1 ↔ LdBPK_313080.1 OG7 LdBPK_270680.1 ↔ LdBPK_313080.1	Both
LTRL590_110007600 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_002772	Both
LTRL590_280006100 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_002772	Both
LTRL590_230006200 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG6 LdBPK_230130.1 ↔ LdBPK_313080.1 OG7 LdBPK_230130.1 ↔ LdBPK_313080.1	Both
LTRL590_310019300 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_311230.1 ↔ LdBPK_313080.1 OG7 LdBPK_311230.1 ↔ LdBPK_313080.1	Both

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