LTRL590_300012400

Phosphatidylinositol-specific phospholipase C, X domain/PDZ domain containing protein, putative
Leishmania tropica L590 OG6: OG6_146793 OG7: OG7_0037550 185 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 185 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_360024700 ⚠
exoribonuclease 2, putative
— Both
LTRL590_060007600 ⚠
5'-3' exonuclease, putative
— Both
LTRL590_260007100
hypothetical protein, conserved
— Both
LTRL590_050006800
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LTRL590_030015300 ⚠
MORN repeat, putative
— Both
LTRL590_220021000
CCR4 associated factor, putative
— Both
LTRL590_040011900
Axonemal dynein light chain, putative
— Both
LTRL590_200016900 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LTRL590_190011700 ⚠
kinesin, putative
— OG6
LTRL590_190011600 ⚠
kinesin, putative
— OG6
LTRL590_300005600
MATH domain containing protein, putative
— Both
LTRL590_280017000
WD domain, G-beta repeat, putative
— Both
LTRL590_280017300
electron-transfer-flavoprotein, alpha polypep
— Both
LTRL590_230025900
alanine racemase, putative
— Both
LTRL590_220008300
SEP domain containing protein, putative
— Both
LTRL590_280019600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_240009000 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_280020100 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_350013100 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_150014000
hypothetical protein, conserved
— Both
LTRL590_120011700 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LTRL590_310006100
ubiquitin hydrolase, putative
— Both
LTRL590_350046200 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LTRL590_350046700 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LTRL590_320008200
hypothetical protein, conserved
— Both
LTRL590_320007600
hypothetical protein, conserved
— Both
LTRL590_320020000
cleavage and polyadenylation specificity fact
— Both
LTRL590_300012700
CDC16, putative
— Both
LTRL590_300027900
endosomal trafficking protein RME-8, putative
— Both
LTRL590_360016100
intraflagellar transport protein IFT122, puta
— Both
LTRL590_360076000 ⚠
ubiquitin-protein ligase, putative
— Both
LTRL590_180016300 ⚠
protein kinase A catalytic subunit
— OG6
LTRL590_330037000 ⚠
transcription elongation factor-like protein
— Both
LTRL590_280028200
tRNA threonylcarbamoyl adenosine modification
— Both
LTRL590_060017200
hypothetical protein, conserved
— Both
LTRL590_090018900
AAA family ATPase, putative
— Both
LTRL590_310007700 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LTRL590_130006200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_130021300 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_010005200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_050015500 ⚠
MORN repeat, putative
— OG7
LTRL590_340029800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LTRL590_340028700 ⚠
Sec7 domain containing protein, putative
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_160018500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_360010800 ⚠
ubiquitin-like protein, putative
— OG7
LTRL590_340045800 ⚠
adaptor gamma-1 chain, putative
— OG7
LTRL590_330024900 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.