LTRL590_220008300

SEP domain containing protein, putative
Leishmania tropica L590 OG6: OG6_102041 OG7: OG7_0005644 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_340041400 ⚠
adenosine kinase-like protein
— OG7
LTRL590_140019500
YjeF family N-terminal domain/YjeF family C-t
— Both
LTRL590_260029200
Zn-finger in Ran binding protein and others/S
— Both
LTRL590_090011100
cyclin 1, putative
— Both
LTRL590_260016900 ⚠
aldo/keto reductase, putative
— Both
LTRL590_360046700
nudix hydrolase-like protein
— Both
LTRL590_290013600 ⚠
U-box domain protein, putative
— Both
LTRL590_250020500
TAP42-like family, putative
— Both
LTRL590_250027400
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LTRL590_290020100 ⚠
carnitine/choline acetyltransferase, putative
— Both
LTRL590_030013100
hypothetical protein, conserved
— Both
LTRL590_320016000
ubiquitin-conjugating enzyme protein, putativ
— Both
LTRL590_320027800 ⚠
Cytidylyltransferase, putative
— Both
LTRL590_310024900
diphthine synthase-like protein
— Both
LTRL590_180015300
UDP-glucose pyrophosphorylase
— Both
LTRL590_340007200 ⚠
CS domain containing protein, putative
— Both
LTRL590_030010900
quinone oxidoreductase, putative
— Both
LTRL590_260024300
deoxyhypusine hydroxylase, putative
— Both
LTRL590_360055500 ⚠
mitochondrial intermediate peptidase, putativ
— Both
LTRL590_340023100
pyroglutamyl-peptidase I (C15 family)
— Both
LTRL590_330005900
hypothetical protein, conserved
— Both
LTRL590_350051600 ⚠
CS domain containing protein, putative
— Both
LTRL590_300032200 ⚠
formate--tetrahydrofolate ligase
— OG6
LTRL590_340043400
phosphomannomutase-like protein
— Both
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— Both
LTRL590_310042000 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
LTRL590_180011900 ⚠
serine/threonine kinase-like protein, putativ
— Both
LTRL590_250019500
NPL4 family, putative
— Both
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_280017300
electron-transfer-flavoprotein, alpha polypep
— Both
LTRL590_220016100 ⚠
ChaC-like protein, putative
— Both
LTRL590_330037000 ⚠
transcription elongation factor-like protein
— Both
LTRL590_280019900 ⚠
hypothetical protein
— OG7
LTRL590_310007700 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LTRL590_300015000 ⚠
adenosine kinase-like protein
— OG7
LTRL590_270033200 ⚠
peptidyl dipeptidase, putative
— OG7
LTRL590_260020800 ⚠
thimet oligopeptidase, putative
— OG7
LTRL590_130011200 ⚠
ubiquitin-like protein
— OG7
LTRL590_220008200 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LTRL590_170016700 ⚠
5'-3' exonuclease, putative
— OG7
LTRL590_000009900 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LTRL590_070005600 ⚠
alpha-adaptin-like protein
— OG7
LTRL590_300014900 ⚠
adenosine kinase, putative
— OG7
LTRL590_300015100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LTRL590_130006200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_190019800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LTRL590_280020000 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_290007900 ⚠
thymine-7-hydroxylase, putative
— OG7
LTRL590_320044900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LTRL590_060010300 ⚠
U-box domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.