LTRL590_300032200

formate--tetrahydrofolate ligase
Leishmania tropica L590 OG6: OG6_100216 OG7: OG7_0002740 198 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 198 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_250028600 ⚠
hypothetical protein, conserved
— Both
LTRL590_110012300 ⚠
hypothetical protein, conserved
— Both
LTRL590_260014700 ⚠
Glucosidase II beta subunit-like/Glucosidase
— Both
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_140020800 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LTRL590_250019500 ⚠
NPL4 family, putative
— OG6
LTRL590_180011900 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LTRL590_200007700 ⚠
deoxyhypusine synthase, putative
— Both
LTRL590_310042000 ⚠
KH domain/Domain of unknown function (DUF1771
— OG6
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— OG6
LTRL590_340043400 ⚠
phosphomannomutase-like protein
— OG6
LTRL590_350051600 ⚠
CS domain containing protein, putative
— OG6
LTRL590_330005900 ⚠
hypothetical protein, conserved
— OG6
LTRL590_340023100 ⚠
pyroglutamyl-peptidase I (C15 family)
— OG6
LTRL590_270018400 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_300039000 ⚠
valyl-tRNA synthetase, putative
— Both
LTRL590_260024300 ⚠
deoxyhypusine hydroxylase, putative
— OG6
LTRL590_030010900 ⚠
quinone oxidoreductase, putative
— OG6
LTRL590_360006500 ⚠
PUB domain containing protein, putative
— Both
LTRL590_340007200 ⚠
CS domain containing protein, putative
— OG6
LTRL590_180015300 ⚠
UDP-glucose pyrophosphorylase
— OG6
LTRL590_300035700 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_340043100 ⚠
hypothetical protein, conserved
— Both
LTRL590_310024900 ⚠
diphthine synthase-like protein
— OG6
LTRL590_350017800 ⚠
monothiol glutaredoxin, putative
— OG6
LTRL590_260029200 ⚠
Zn-finger in Ran binding protein and others/S
— OG6
LTRL590_360073200 ⚠
disgorgin, putative
— Both
LTRL590_350052400 ⚠
Cysteine-rich motif following a subset of SET
— Both
LTRL590_320005700 ⚠
N-myristoyl transferase, putative
— OG6
LTRL590_180006000 ⚠
alpha glucosidase II subunit, putative
— Both
LTRL590_330013200 ⚠
WD domain, G-beta repeat, putative
— OG6
LTRL590_320033900 ⚠
superoxide dismutase, putative
— OG6
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— Both
LTRL590_180014200 ⚠
cyclosporin 16, putative
— OG6
LTRL590_310006100 ⚠
ubiquitin hydrolase, putative
— OG6
LTRL590_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG6
LTRL590_350005300 ⚠
pyruvate kinase
— OG6
LTRL590_140019500 ⚠
YjeF family N-terminal domain/YjeF family C-t
— OG6
LTRL590_250027400 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
LTRL590_320016000 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG6
LTRL590_320027800 ⚠
Cytidylyltransferase, putative
— OG6
LTRL590_030013100 ⚠
hypothetical protein, conserved
— OG6
LTRL590_290020100 ⚠
carnitine/choline acetyltransferase, putative
— OG6
LTRL590_280031200 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LTRL590_360079900 ⚠
hypothetical protein, conserved
— OG6
LTRL590_140021400 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LTRL590_050008000 ⚠
monothiol glutaredoxin, putative
— OG6
LTRL590_130015300 ⚠
leucyl-tRNA synthetase, putative
— Both
LTRL590_290013600 ⚠
U-box domain protein, putative
— OG6
LTRL590_250020500 ⚠
TAP42-like family, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.