LTRL590_350005300

pyruvate kinase
Leishmania tropica L590 OG6: OG6_100258 OG7: OG7_0002165 190 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 190 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— Both
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_140019500 ⚠
YjeF family N-terminal domain/YjeF family C-t
— Both
LTRL590_010005200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_060014000 ⚠
dihydrofolate reductase-thymidylate synthase
— Both
LTRL590_010010400 ⚠
hypothetical protein
— Both
LTRL590_300036200 ⚠
S-adenosylmethionine synthetase
— Both
LTRL590_110013400 ⚠
Cytosol aminopeptidase family, catalytic doma
— Both
LTRL590_010010100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LTRL590_010009700 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LTRL590_150021100 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— Both
LTRL590_340038800 ⚠
aldose 1-epimerase-like protein
— Both
LTRL590_350017100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LTRL590_350017000 ⚠
NADH-dependent fumarate reductase, putative
— Both
LTRL590_290014800 ⚠
guanine deaminase, putative
— Both
LTRL590_070014900 ⚠
flavoprotein subunit-like protein
— Both
LTRL590_180021100 ⚠
nonspecific nucleoside hydrolase
— Both
LTRL590_350054300 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LTRL590_360031500 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LTRL590_010009900 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LTRL590_150020600 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LTRL590_270014900 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
LTRL590_150021200 ⚠
cAMP specific phosphodiesterase, putative
— Both
LTRL590_030007100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LTRL590_320041100 ⚠
glucosamine-6-phosphate isomerase, putative
— Both
LTRL590_000006000 ⚠
aminopeptidase, putative
— Both
LTRL590_140006300 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LTRL590_130016200 ⚠
adenylosuccinate synthetase, putative
— Both
LTRL590_320005700 ⚠
N-myristoyl transferase, putative
— Both
LTRL590_310006100 ⚠
ubiquitin hydrolase, putative
— Both
LTRL590_340043400 ⚠
phosphomannomutase-like protein
— Both
LTRL590_330015700 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LTRL590_330037000 ⚠
transcription elongation factor-like protein
— Both
LTRL590_120011000 ⚠
glucose-6-phosphate isomerase
— Both
LTRL590_060016200 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LTRL590_120013400 ⚠
hypothetical protein
— Both
LTRL590_200022000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_310018200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_000029000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_200022100 ⚠
Peptidase family M20/M25/M40, putative
— Both
LTRL590_000028900 ⚠
amidohydrolase, putative
— Both
LTRL590_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LTRL590_300020100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_000028800 ⚠
Peptidase dimerisation domain/Peptidase famil
— Both
LTRL590_010006700 ⚠
cyclophilin 12, putative
— OG6
LTRL590_270012500 ⚠
UBA/TS-N domain containing protein, putative
— Both
LTRL590_310007700 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LTRL590_130006200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_130021300 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_280019800 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.