LTRL590_000029000

N-acyl-L-amino acid amidohydrolase, putative

Leishmania tropica L590 OG6: OG6_101553 OG7: OG7_0005942 172 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 172 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_110013400 ⚠ Cytosol aminopeptidase family, catalytic doma	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LTRL590_000006000 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LTRL590_280008300 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_280470.1 OG6 LdBPK_201740.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 +1 more	Both
LTRL590_280009400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	Both
LTRL590_040008100 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	OG7
LTRL590_360068100 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_310018100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	OG7
LTRL590_350017200 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LTRL590_000027600 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_332020.1 OG6 LdBPK_201740.1 ↔ LdBPK_332020.1 OG7 LdBPK_201720.1 ↔ LdBPK_332020.1 OG7 LdBPK_201740.1 ↔ LdBPK_332020.1	Both
LTRL590_310022300 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_311440.1 OG6 LdBPK_201740.1 ↔ LdBPK_311440.1 OG7 LdBPK_201720.1 ↔ LdBPK_311440.1 OG7 LdBPK_201740.1 ↔ LdBPK_311440.1	Both
LTRL590_260016400 ⚠ RNA pseudouridylate synthase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_261140.1 OG6 LdBPK_201740.1 ↔ LdBPK_261140.1 OG7 LdBPK_201720.1 ↔ LdBPK_261140.1 OG7 LdBPK_201740.1 ↔ LdBPK_261140.1	Both
LTRL590_200022100 ⚠ Peptidase family M20/M25/M40, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LTRL590_330030900 ⚠ glycosyl hydrolase-like protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_332390.1 OG6 LdBPK_201740.1 ↔ LdBPK_332390.1 OG7 LdBPK_201720.1 ↔ LdBPK_332390.1 OG7 LdBPK_201740.1 ↔ LdBPK_332390.1	Both
LTRL590_350025100 ⚠ U3 small nucleolar RNA-associated protein 6,	—	OG6 LdBPK_201720.1 ↔ LdBPK_351980.1 OG6 LdBPK_201740.1 ↔ LdBPK_351980.1 OG7 LdBPK_201720.1 ↔ LdBPK_351980.1 OG7 LdBPK_201740.1 ↔ LdBPK_351980.1	Both
LTRL590_350028100 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_352320.1 OG6 LdBPK_201740.1 ↔ LdBPK_352320.1	OG6
LTRL590_000028900 ⚠ amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LTRL590_360037400 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LTRL590_350052400 ⚠ Cysteine-rich motif following a subset of SET	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LTRL590_360074900 ⚠ flagellum transition zone component, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_366480.1 OG6 LdBPK_201740.1 ↔ LdBPK_366480.1 OG7 LdBPK_201720.1 ↔ LdBPK_366480.1 OG7 LdBPK_201740.1 ↔ LdBPK_366480.1	Both
LTRL590_330021400 ⚠ protein kinase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_331490.1 OG6 LdBPK_201740.1 ↔ LdBPK_331490.1 OG7 LdBPK_201720.1 ↔ LdBPK_331490.1 OG7 LdBPK_201740.1 ↔ LdBPK_331490.1	Both
LTRL590_220010300 ⚠ Rab-GTPase-TBC domain containing protein, put	—	OG6 LdBPK_201720.1 ↔ LdBPK_220400.1 OG6 LdBPK_201740.1 ↔ LdBPK_220400.1 OG7 LdBPK_201720.1 ↔ LdBPK_220400.1 OG7 LdBPK_201740.1 ↔ LdBPK_220400.1	Both
LTRL590_300025800 ⚠ calpain-like cysteine peptidase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_302040.1 OG6 LdBPK_201740.1 ↔ LdBPK_302040.1	OG6
LTRL590_300010400 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_300480.1 OG6 LdBPK_201740.1 ↔ LdBPK_300480.1 OG7 LdBPK_201720.1 ↔ LdBPK_300480.1 OG7 LdBPK_201740.1 ↔ LdBPK_300480.1	Both
LTRL590_260017000 ⚠ Leucine rich repeat, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_261200.1 OG6 LdBPK_201740.1 ↔ LdBPK_261200.1 OG7 LdBPK_201720.1 ↔ LdBPK_261200.1 OG7 LdBPK_201740.1 ↔ LdBPK_261200.1	Both
LTRL590_250016800 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_251070.1 OG6 LdBPK_201740.1 ↔ LdBPK_251070.1 OG7 LdBPK_201720.1 ↔ LdBPK_251070.1 OG7 LdBPK_201740.1 ↔ LdBPK_251070.1	Both
LTRL590_300020100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LTRL590_260017700 ⚠ Cupin-like domain containing protein, putativ	—	OG6 LdBPK_201720.1 ↔ LdBPK_261270.1 OG6 LdBPK_201740.1 ↔ LdBPK_261270.1 OG7 LdBPK_201720.1 ↔ LdBPK_261270.1 OG7 LdBPK_201740.1 ↔ LdBPK_261270.1	Both
LTRL590_290019400 ⚠ Hsp70 protein/TPR repeat, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_291330.1 OG6 LdBPK_201740.1 ↔ LdBPK_291330.1 OG7 LdBPK_201720.1 ↔ LdBPK_291330.1 OG7 LdBPK_201740.1 ↔ LdBPK_291330.1	Both
LTRL590_000028800 ⚠ Peptidase dimerisation domain/Peptidase famil	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LTRL590_330017400 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_008414	Both
LTRL590_340006300 ⚠ lactate/malate dehydrogenase, NAD binding dom	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LTRL590_340006400 ⚠ lactate/malate dehydrogenase, alpha/beta C-te	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LTRL590_340006600 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LTRL590_290027800 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_201720.1 OG7 LdBPK_130530.1 ↔ LdBPK_201740.1	OG7
LTRL590_170010700 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LTRL590_340030800 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LTRL590_340039900 ⚠ ruvb-like 1 DNA helicase, putative	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	OG7
LTRL590_260018500 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LTRL590_350059100 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LTRL590_050009100 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LTRL590_330032400 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LTRL590_030005400 ⚠ Met-10+ like-protein, putative	—	OG7 LdBPK_160320.1 ↔ LdBPK_201720.1 OG7 LdBPK_160320.1 ↔ LdBPK_201740.1	OG7
LTRL590_190011900 ⚠ glycosomal malate dehydrogenase	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	OG7
LTRL590_340006200 ⚠ malate dehydrogenase, putative	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	OG7
LTRL590_340006500 ⚠ malate dehydrogenase, putative	—	OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	OG7
LTRL590_360077600 ⚠ protein transport protein Sec23-like protein	—	OG7 LdBPK_100330.1 ↔ LdBPK_201720.1 OG7 LdBPK_100330.1 ↔ LdBPK_201740.1	OG7
LTRL590_050011500 ⚠ CYC2-like cyclin, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_241960.1 OG7 LdBPK_201740.1 ↔ LdBPK_241960.1	OG7
LTRL590_300012500 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_008414 ↔ TCSYLVIO_010327	OG7
LTRL590_080005700 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	OG7

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