LTRL590_190011900

glycosomal malate dehydrogenase
Leishmania tropica L590 OG6: OG6_133291 OG7: OG7_0004751 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_040010700 ⚠
spermidine synthase
— OG7
LTRL590_300020100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_260020800 ⚠
thimet oligopeptidase, putative
— OG7
LTRL590_270033200 ⚠
peptidyl dipeptidase, putative
— OG7
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— OG7
LTRL590_290028200 ⚠
conserved hypothetical protein, putative
— OG7
LTRL590_130010700 ⚠
Metallopeptidase family M24, putative
— OG7
LTRL590_190006200 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LTRL590_010013800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_000028800 ⚠
Peptidase dimerisation domain/Peptidase famil
— OG7
LTRL590_010013900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_010014200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_010014600 ⚠
Peptidase family M3, putative
— OG7
LTRL590_090013200 ⚠
oligopeptidase b
— OG7
LTRL590_230023700 ⚠
aminoacyclase, putative
— OG7
LTRL590_360081200 ⚠
prolyl oligopeptidase, putative
— OG7
LTRL590_000028900 ⚠
amidohydrolase, putative
— OG7
LTRL590_050008300 ⚠
trypanothione reductase
— OG7
LTRL590_200022100 ⚠
Peptidase family M20/M25/M40, putative
— OG7
LTRL590_000029000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_310018200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_280021900 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LTRL590_150008300 ⚠
ecotin, putative
— OG7
LTRL590_150010200 ⚠
ecotin, putative
— OG7
LTRL590_150010100 ⚠
ecotin, putative
— OG7
LTRL590_360079200 ⚠
y113g7b.23 protein-like protein
— OG7
LTRL590_290008400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_220010400 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LTRL590_220020600 ⚠
ser/thr protein phosphatase, putative
— OG7
LTRL590_170010200 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LTRL590_280022200 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LTRL590_010014100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_210023600 ⚠
RNA helicase, putative
— OG7
LTRL590_010013300 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LTRL590_000015800 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LTRL590_350008800 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LTRL590_330033600 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LTRL590_010014400 ⚠
hypothetical protein
— OG7
LTRL590_360055500 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LTRL590_010014500 ⚠
Peptidase family M3, putative
— OG7
LTRL590_360027500 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG7
LTRL590_000009500 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LTRL590_260006100 ⚠
adenine phosphoribosyltransferase
— OG7
LTRL590_360080100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LTRL590_330037200 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LTRL590_110008000 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LTRL590_150005400 ⚠
cytochrome-b5 reductase, putative
— OG7
LTRL590_270012700 ⚠
reductase, putative
— OG7
LTRL590_320030700 ⚠
cytochrome-b5 reductase, putative
— OG7
LTRL590_140009200 ⚠
threonine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.