LTRL590_000028800

Peptidase dimerisation domain/Peptidase family M20/M25/M40, putative
Leishmania tropica L590 OG6: OG6_101553 OG7: OG7_0005942 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_110013400 ⚠
Cytosol aminopeptidase family, catalytic doma
— +9 more Both
LTRL590_000006000 ⚠
aminopeptidase, putative
— +9 more Both
LTRL590_330034200 ⚠
aminopeptidase, putative
— +7 more Both
LTRL590_280008300 ⚠
rrp44p homologue, putative
— +1 more Both
LTRL590_280009400 ⚠
DIS3-like exonuclease, putative
— Both
LTRL590_040008100 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LTRL590_360068100 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LTRL590_310018100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_290028700 ⚠
protein kinase, putative
— Both
LTRL590_260009300 ⚠
hypothetical protein, conserved
— Both
LTRL590_350048400 ⚠
elongation factor 1-alpha, putative
— Both
LTRL590_300020900 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— Both
LTRL590_350017200 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LTRL590_000027600 ⚠
Ribosome assembly protein rrb1, putative
— Both
LTRL590_310022300 ⚠
hypothetical protein, conserved
— Both
LTRL590_260016400 ⚠
RNA pseudouridylate synthase, putative
— Both
LTRL590_330030900 ⚠
glycosyl hydrolase-like protein
— Both
LTRL590_350025100 ⚠
U3 small nucleolar RNA-associated protein 6,
— Both
LTRL590_350028100 ⚠
ATP-dependent RNA helicase-like protein
— OG6
LTRL590_360037400 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LTRL590_350052400 ⚠
Cysteine-rich motif following a subset of SET
— Both
LTRL590_360074900 ⚠
flagellum transition zone component, putative
— Both
LTRL590_330021400 ⚠
protein kinase, putative
— Both
LTRL590_220010300 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LTRL590_300025800 ⚠
calpain-like cysteine peptidase, putative
— OG6
LTRL590_300010400 ⚠
hypothetical protein, conserved
— Both
LTRL590_260017000 ⚠
Leucine rich repeat, putative
— Both
LTRL590_250016800 ⚠
hypothetical protein, conserved
— Both
LTRL590_260017700 ⚠
Cupin-like domain containing protein, putativ
— Both
LTRL590_290019400 ⚠
Hsp70 protein/TPR repeat, putative
— Both
LTRL590_330017400 ⚠
hypothetical protein, conserved
— Both
LTRL590_340006300 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LTRL590_340006400 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
LTRL590_340006600 ⚠
malate dehydrogenase
— Both
LTRL590_290027800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170010700 ⚠
Acyl CoA binding protein, putative
— OG7
LTRL590_340030800 ⚠
acyl-CoA binding protein, putative
— OG7
LTRL590_340039900 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LTRL590_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LTRL590_350059100 ⚠
GTP-binding protein, putative
— OG7
LTRL590_050009100 ⚠
GTPase, putative
— OG7
LTRL590_330032400 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_030005400 ⚠
Met-10+ like-protein, putative
— OG7
LTRL590_190011900 ⚠
glycosomal malate dehydrogenase
— OG7
LTRL590_340006200 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_340006500 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_360077600 ⚠
protein transport protein Sec23-like protein
— OG7
LTRL590_050011500 ⚠
CYC2-like cyclin, putative
— OG7
LTRL590_300012500 ⚠
nuclear movement protein, putative
— OG7
LTRL590_080005700 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.