LTRL590_360068100

isoleucyl-tRNA synthetase, putative

Leishmania tropica L590 OG6: OG6_100811 OG7: OG7_0003029 197 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 197 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_310018200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_000029000 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_200022000 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_200022100 ⚠ Peptidase family M20/M25/M40, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_110013400 ⚠ Cytosol aminopeptidase family, catalytic doma	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LTRL590_000006000 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LTRL590_340027400 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
LTRL590_130015300 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LTRL590_220009800 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LTRL590_160018300 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LTRL590_120013400 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_000028900 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_230023700 ⚠ aminoacyclase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	OG7
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LTRL590_140021400 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 Tb927.10.9190 ↔ Tb927.8.5330	Both
LTRL590_310018100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	OG7
LTRL590_300020100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_000028800 ⚠ Peptidase dimerisation domain/Peptidase famil	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LTRL590_040008100 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LTRL590_200007200 ⚠ kelch domain-containing protein	—	OG7 LdBPK_220850.1 ↔ LdBPK_365870.1	OG7
LTRL590_110007200 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LTRL590_320048000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004705	Both
LTRL590_290011700 ⚠ NF-X1 type zinc finger containing protein, pu	—	OG6 LdBPK_290620.1 ↔ LdBPK_365870.1 OG7 LdBPK_290620.1 ↔ LdBPK_365870.1	Both
LTRL590_120008100 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1 OG7 LdBPK_120105.1 ↔ LdBPK_365870.1	Both
LTRL590_250010000 Translation initiation factor SUI1, putative	—	OG6 LdBPK_250420.1 ↔ LdBPK_365870.1 OG7 LdBPK_250420.1 ↔ LdBPK_365870.1	Both
LTRL590_280009400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	Both
LTRL590_220019900 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004705	Both
LTRL590_220012500 hypothetical protein, conserved	—	OG6 LdBPK_220710.1 ↔ LdBPK_365870.1 OG7 LdBPK_220710.1 ↔ LdBPK_365870.1	Both
LTRL590_350051500 ⚠ sm-f snRNP core complex protein, putative	—	OG6 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_301270.1 ↔ LdBPK_365870.1	Both
LTRL590_300012900 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_004705	Both
LTRL590_360005600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004705	OG6
LTRL590_270031400 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004705	OG6
LTRL590_140020800 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
LTRL590_190012800 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006012	Both
LTRL590_360063100 VHS domain containing protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008292 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008292	Both
LTRL590_360051200 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008197	Both
LTRL590_290005600 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010724	Both
LTRL590_290033300 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004998	Both
LTRL590_350019500 peroxisome targeting signal 1 receptor, putat	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005361 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005361	Both
LTRL590_350015600 protein kinase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005149	OG6
LTRL590_250007300 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005414	Both
LTRL590_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007603	Both
LTRL590_250031800 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010323	Both
LTRL590_250028600 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006404	Both
LTRL590_210011100 la RNA binding protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006827 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006827	Both
LTRL590_280031200 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
LTRL590_270019200 arginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005509 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005509	Both

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