LTRL590_050008300

trypanothione reductase
Leishmania tropica L590 OG6: OG6_101659 OG7: OG7_0001626 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_340006200 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_090013200 ⚠
oligopeptidase b
— Both
LTRL590_300020100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_000028800 ⚠
Peptidase dimerisation domain/Peptidase famil
— Both
LTRL590_340030900 ⚠
ATP-dependent DNA helicase, putative
— Both
LTRL590_270031400 ⚠
TPR-repeat protein, putative
— OG6
LTRL590_360005600 ⚠
stress-inducible protein STI1 homolog
— OG6
LTRL590_340006300 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LTRL590_340006400 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
LTRL590_340006600 ⚠
malate dehydrogenase
— Both
LTRL590_200011700
cytidine triphosphate synthase, putative
— Both
LTRL590_340039900 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LTRL590_190011900 ⚠
glycosomal malate dehydrogenase
— OG7
LTRL590_000028900 ⚠
amidohydrolase, putative
— Both
LTRL590_340006500 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_310018100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_010014100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360081200 ⚠
prolyl oligopeptidase, putative
— OG7
LTRL590_230023700 ⚠
aminoacyclase, putative
— OG7
LTRL590_300035700 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_010014200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_010013900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_010013800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_260007600 ⚠
aminopeptidase-like protein
— OG7
LTRL590_360067400 ⚠
aminopeptidase P1, putative
— OG7
LTRL590_120014700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LTRL590_290030000 ⚠
aminopeptidase, putative
— Both
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— Both
LTRL590_260027900
kynureninase, putative
— Both
LTRL590_140019200
enolase
— Both
LTRL590_300036200
S-adenosylmethionine synthetase
— Both
LTRL590_350036800
glycerol kinase, glycosomal, putative
— Both
LTRL590_300038400
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
LTRL590_050012800
methylthioadenosine phosphorylase, putative
— Both
LTRL590_320037400
nucleoside diphosphate kinase b
— Both
LTRL590_240008200 ⚠
fumarate hydratase, putative
— Both
LTRL590_230008300
pteridine reductase 1
— Both
LTRL590_350039500
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LTRL590_290014800
guanine deaminase, putative
— Both
LTRL590_290028200 ⚠
conserved hypothetical protein, putative
— Both
LTRL590_330020200
glutamine aminotransferase, putative
— Both
LTRL590_290026600 ⚠
fumarate hydratase, putative
— Both
LTRL590_350028900 ⚠
aminopeptidase P, putative
— Both
LTRL590_060008500 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LTRL590_140016400
Sodium/hydrogen exchanger family, putative
— Both
LTRL590_120013400 ⚠
hypothetical protein
— Both
LTRL590_330029600 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_200022000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_310018200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LTRL590_000029000 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.