LTRL590_290026600

fumarate hydratase, putative
Leishmania tropica L590 OG6: OG6_102839 OG7: OG7_0008166 32 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 32 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_290028600 ⚠
C-8 sterol isomerase-like protein
— Both
LTRL590_360063500 ⚠
aldehyde dehydrogenase, putative
— OG7
LTRL590_320037400 ⚠
nucleoside diphosphate kinase b
— Both
LTRL590_140006300 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LTRL590_350054300 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LTRL590_040009300 ⚠
adenylosuccinate lyase, putative
— Both
LTRL590_180021100 ⚠
nonspecific nucleoside hydrolase
— Both
LTRL590_290014800 ⚠
guanine deaminase, putative
— Both
LTRL590_350039500 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LTRL590_150016600 ⚠
glutamate dehydrogenase
— Both
LTRL590_240028600 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LTRL590_050012800 ⚠
methylthioadenosine phosphorylase, putative
— Both
LTRL590_300041400 ⚠
aldehyde dehydrogenase, putative
— Both
LTRL590_350036800 ⚠
glycerol kinase, glycosomal, putative
— Both
LTRL590_300036200 ⚠
S-adenosylmethionine synthetase
— Both
LTRL590_240028300 ⚠
transketolase
— Both
LTRL590_130016200 ⚠
adenylosuccinate synthetase, putative
— Both
LTRL590_240008200 ⚠
fumarate hydratase, putative
— Both
LTRL590_120011900 ⚠
alanine aminotransferase
— Both
LTRL590_180010400 ⚠
aconitase, putative
— Both
LTRL590_050008300 ⚠
trypanothione reductase
— Both
LTRL590_140019200 ⚠
enolase
— Both
LTRL590_360031500 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LTRL590_320038700 ⚠
protein phosphatase 2A catalytic subunit, put
— OG6
LTRL590_280034300 ⚠
protein phosphatase 4 catalytic subunit, puta
— OG6
LTRL590_140010300 ⚠
cystathionine beta-lyase-like protein
— Both
LTRL590_360024400 ⚠
aldehyde dehydrogenase, putative
— Both
LTRL590_350038400 ⚠
cystathione gamma lyase, putative
— Both
LTRL590_180012400 ⚠
citrate synthase, putative
— Both
LTRL590_240013500 ⚠
malic enzyme, putative
— Both
LTRL590_180012300 ⚠
citrate synthase, putative
— Both
LTRL590_240013400 ⚠
malic enzyme, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.