LTRL590_150016600

glutamate dehydrogenase
Leishmania tropica L590 OG6: OG6_106160 OG7: OG7_0011174 123 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 123 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_290013400 ⚠
heat shock protein 90, putative
— +6 more Both
LTRL590_330032300 ⚠
heat shock protein, putative
— +1 more OG7
LTRL590_190019800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LTRL590_300037000
MORN repeat, putative
— Both
LTRL590_110017400
pyruvate phosphate dikinase, putative
— Both
LTRL590_070011600
hypothetical protein, conserved
— Both
LTRL590_360049400
S-adenosylhomocysteine hydrolase
— Both
LTRL590_300029000
SET domain containing protein, putative
— Both
LTRL590_320023700
hypothetical protein, conserved
— Both
LTRL590_090018500 ⚠
hypothetical protein, conserved
— Both
LTRL590_080013200
Beta-lactamase superfamily domain containing
— Both
LTRL590_050015500 ⚠
MORN repeat, putative
— Both
LTRL590_090015200
hypothetical protein, conserved
— Both
LTRL590_350036800
glycerol kinase, glycosomal, putative
— Both
LTRL590_240008200 ⚠
fumarate hydratase, putative
— Both
LTRL590_290026600 ⚠
fumarate hydratase, putative
— Both
LTRL590_320014900
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LTRL590_040008300
hypothetical protein, conserved
— Both
LTRL590_320037400
nucleoside diphosphate kinase b
— Both
LTRL590_170014900
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LTRL590_040009100 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LTRL590_200017700 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LTRL590_350019400
threonyl-tRNA synthetase, putative
— Both
LTRL590_060006700
hypothetical protein, conserved
— Both
LTRL590_130005000
WD40 repeats, putative
— Both
LTRL590_230005400 ⚠
peroxidoxin
— Both
LTRL590_150017000 ⚠
tryparedoxin peroxidase
— Both
LTRL590_150015600
protein phosphatase 2A regulatory subunit, pu
— Both
LTRL590_010009300 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LTRL590_020012400 ⚠
gamma-glutamyl phosphate reductase-like prote
— OG7
LTRL590_020012100 ⚠
gamma-glutamyl phosphate reductase-like prote
— OG7
LTRL590_220008200 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_340037800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LTRL590_170006700 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_140021400 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LTRL590_210009500 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LTRL590_300018300 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_330038900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_240011900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_210014300 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LTRL590_330038800 ⚠
hypothetical protein
— OG7
LTRL590_340028800 ⚠
Elongation factor Tu GTP binding domain conta
— OG7
LTRL590_320013300 ⚠
cyclin 9, putative
— OG7
LTRL590_360054700 ⚠
ubiquitin protein ligase, putative
— OG7
LTRL590_350056900 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LTRL590_350014600 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LTRL590_360056800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.