LTRL590_110017400

pyruvate phosphate dikinase, putative
Leishmania tropica L590 OG6: OG6_100727 OG7: OG7_0004964 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_140021300
inositol-3-phosphate synthase
— Both
LTRL590_190019600 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LTRL590_270014900
isovaleryl-coA dehydrogenase, putative
— Both
LTRL590_360024400
aldehyde dehydrogenase, putative
— Both
LTRL590_150005000 ⚠
histone H4
— Both
LTRL590_350018400 ⚠
Core histone H2A/H2B/H3/H4, putative
— Both
LTRL590_350005100 ⚠
histone H4
— Both
LTRL590_060005000 ⚠
Core histone H2A/H2B/H3/H4, putative
— Both
LTRL590_010011600
DNA-damage inducible protein DDI1-like protei
— Both
LTRL590_030006500
hypothetical protein, conserved
— Both
LTRL590_360040500
ATP synthase, putative
— Both
LTRL590_350013200 ⚠
NADH-dependent fumarate reductase, putative
— Both
LTRL590_060008800
glutamine synthetase, putative
— Both
LTRL590_340042200
vacuolar ATP synthase catalytic subunit A, pu
— Both
LTRL590_260005200
pyridoxal phosphate containing glycine decarb
— Both
LTRL590_350017100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LTRL590_350017000 ⚠
NADH-dependent fumarate reductase, putative
— Both
LTRL590_230005400 ⚠
peroxidoxin
— Both
LTRL590_150016600
glutamate dehydrogenase
— Both
LTRL590_230009000
(H+)-ATPase G subunit, putative
— Both
LTRL590_150017000 ⚠
tryparedoxin peroxidase
— Both
LTRL590_070014900 ⚠
flavoprotein subunit-like protein
— Both
LTRL590_360049400
S-adenosylhomocysteine hydrolase
— Both
LTRL590_280031900
vacuolar ATP synthase subunit b, putative
— Both
LTRL590_340005700
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LTRL590_030006800
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LTRL590_040017400
hypothetical protein, conserved
— Both
LTRL590_210007900 ⚠
hexokinase, putative
— Both
LTRL590_210008000 ⚠
Hexokinase, putative
— Both
LTRL590_170010700 ⚠
Acyl CoA binding protein, putative
— OG7
LTRL590_340030800 ⚠
acyl-CoA binding protein, putative
— OG7
LTRL590_310018100 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LTRL590_240026400 ⚠
cyclin 11, putative
— OG7
LTRL590_280009400 ⚠
DIS3-like exonuclease, putative
— OG7
LTRL590_340023300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_310041000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_300043000 ⚠
CYC2-like protein, putative
— OG7
LTRL590_110010100 ⚠
chromatin binding protein, putative
— OG7
LTRL590_170006800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360051400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360034600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LTRL590_100009700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LTRL590_230023700 ⚠
aminoacyclase, putative
— OG7
LTRL590_330013900 ⚠
G1 cyclin CycE4, putative
— OG7
LTRL590_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LTRL590_330032400 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_050009100 ⚠
GTPase, putative
— OG7
LTRL590_350059100 ⚠
GTP-binding protein, putative
— OG7
LTRL590_050011500 ⚠
CYC2-like cyclin, putative
— OG7
LTRL590_360010800 ⚠
ubiquitin-like protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.