LTRL590_010011600

DNA-damage inducible protein DDI1-like protein

Leishmania tropica L590 OG6: OG6_101685 OG7: OG7_0006273 201 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 201 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_000006000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
LTRL590_110013400 ⚠ Cytosol aminopeptidase family, catalytic doma	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG6 LdBPK_010630.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG7 LdBPK_010630.1 ↔ LdBPK_110630.1 OG7 LdBPK_010630.1 ↔ LdBPK_332700.1 +1 more	Both
LTRL590_190019600 ⚠ FK506-binding protein (FKBP)-type peptidyl-pr	—	OG7 LdBPK_010630.1 ↔ LdBPK_291330.1	OG7
LTRL590_000027600 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005619	Both
LTRL590_280009400 ⚠ DIS3-like exonuclease, putative	—	OG7 LdBPK_010630.1 ↔ LdBPK_280470.1	OG7
LTRL590_350059100 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_010630.1 ↔ LdBPK_050200.1	OG7
LTRL590_260018500 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_010630.1 ↔ LdBPK_050200.1	OG7
LTRL590_240026400 ⚠ cyclin 11, putative	—	OG7 LdBPK_010630.1 ↔ LdBPK_241960.1	OG7
LTRL590_310018100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG7 LdBPK_010630.1 ↔ LdBPK_201720.1 OG7 LdBPK_010630.1 ↔ LdBPK_201740.1	OG7
LTRL590_350028800 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	OG7
LTRL590_360006700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004468	OG7
LTRL590_110007200 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003428	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003428	Both
LTRL590_220011500 guide RNA associated protein, GAP2, putative	—	OG6 TCSYLVIO_001262 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_003428	Both
LTRL590_360076300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	Both
LTRL590_230012300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	Both
LTRL590_240027900 tubulin folding cofactor D, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003428	Both
LTRL590_300011300 hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003428	Both
LTRL590_130013600 N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_003428	Both
LTRL590_300018600 Zinc finger, C3HC4 type (RING finger) contain	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_003428	Both
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003867	Both
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003867	Both
LTRL590_150008100 ribonucleoprotein p18, mitochondrial precurso	—	OG6 TCSYLVIO_002426 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_003428	Both
LTRL590_220010900 Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_003428	Both
LTRL590_240026600 WD domain, G-beta repeat/PFU (PLAA family ubi	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_003428	Both
LTRL590_250029600 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006413 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006413	Both
LTRL590_360081400 ⚠ beta-adaptin, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_004597 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004597	Both
LTRL590_310021700 hypothetical protein, conserved	—	OG7 TCSYLVIO_002919 ↔ TCSYLVIO_003428	OG7
LTRL590_320007200 Histone chaperone Rttp106-like, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006113 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006113	Both
LTRL590_210025600 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009362 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009362	Both
LTRL590_350017100 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
LTRL590_340047000 GRIP domain containing protein, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003707 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003707	Both
LTRL590_230008300 pteridine reductase 1	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_008848	Both
LTRL590_350017000 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
LTRL590_340008200 ⚠ tRNA pseudouridine synthase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_004376 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004376	Both
LTRL590_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_007603	Both
LTRL590_190014500 phenylalanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005548	Both
LTRL590_350019400 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_007511	Both
LTRL590_190007100 C-terminal motor kinesin, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006065	OG6
LTRL590_180010800 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006181 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006181	Both
LTRL590_350013900 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005125 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005125	Both
LTRL590_070014500 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_004468 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004468	Both
LTRL590_200008100 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003428	Both
LTRL590_260024200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003586	Both
LTRL590_100013800 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003586	Both
LTRL590_350039800 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005810	Both
LTRL590_050006700 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009880	Both
LTRL590_000023500 Exonuclease, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_010944	Both
LTRL590_180008800 ATP12 chaperone protein, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006163 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006163	Both

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