LTRL590_240027900

tubulin folding cofactor D, putative

Leishmania tropica L590 OG6: OG6_102599 OG7: OG7_0006853 213 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 213 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_230012300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	Both
LTRL590_200008100 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	Both
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003107 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003107	Both
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003107 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003107	Both
LTRL590_350028800 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	OG7
LTRL590_080009500 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
LTRL590_180017800 ⚠ Prolyl-tRNA synthetase, C-terminal, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LTRL590_180017700 ⚠ bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LTRL590_190014500 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005548	Both
LTRL590_240005100 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 LdBPK_240010.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 +1 more	Both
LTRL590_340044700 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	OG7
LTRL590_300011300 hypothetical protein, conserved	—	OG6 LdBPK_242100.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003118 OG7 LdBPK_242100.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003118	Both
LTRL590_120007800 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006977	Both
LTRL590_340027400 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 +1 more	Both
LTRL590_360076300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	Both
LTRL590_000006000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_001670 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001670	Both
LTRL590_180011300 ⚠ Zn-finger in Ran binding protein and others/F	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LTRL590_190019100 ⚠ eukaryotic translation initiation factor-like	—	OG7 LdBPK_242100.1 ↔ LdBPK_300460.1	OG7
LTRL590_140019300 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LTRL590_360060300 ⚠ Leucine rich repeat, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_261200.1	OG7
LTRL590_260017400 ⚠ FYVE zinc finger containing protein, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LTRL590_050013000 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006138	OG7
LTRL590_360080800 ⚠ replication factor C, subunit 5, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_200016600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_170009800 ⚠ ATPase family associated with various cellula	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_150012000 hypothetical protein, conserved	—	OG6 LdBPK_150690.1 ↔ LdBPK_242100.1 OG7 LdBPK_150690.1 ↔ LdBPK_242100.1	Both
LTRL590_350038600 ⚠ replication factor C, subunit 3, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_300032500 ⚠ replication factor C, subunit 2, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_270010700 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LTRL590_300015300 ⚠ ubiquitin-protein ligase, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LTRL590_350061200 ⚠ SPRY domain/HECT-domain (ubiquitin-transferas	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LTRL590_300017100 ⚠ WW domain containing protein, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LTRL590_070008400 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LTRL590_240010200 Leucine Rich repeats (2 copies)/Leucine rich	—	OG6 LdBPK_240500.1 ↔ LdBPK_242100.1 OG7 LdBPK_240500.1 ↔ LdBPK_242100.1	Both
LTRL590_220011500 guide RNA associated protein, GAP2, putative	—	OG6 TCSYLVIO_001262 ↔ TCSYLVIO_001302 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_001302	Both
LTRL590_180015900 5-oxoprolinase, putative	—	OG6 LdBPK_181050.1 ↔ LdBPK_242100.1 OG7 LdBPK_181050.1 ↔ LdBPK_242100.1	Both
LTRL590_250029600 hypothetical protein, conserved	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006413 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006413	Both
LTRL590_180008800 ATP12 chaperone protein, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006163 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006163	Both
LTRL590_300038100 hypothetical protein, conserved	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003353 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003353	Both
LTRL590_210026900 ATP synthase F1 subunit gamma protein, putati	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009375	Both
LTRL590_070014900 ⚠ flavoprotein subunit-like protein	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005116 +2 more	Both
LTRL590_350039800 hypothetical protein, conserved	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005810	Both
LTRL590_000023500 Exonuclease, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010944	Both
LTRL590_050006700 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009880	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_001709 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001709	Both
LTRL590_350019400 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007511	Both
LTRL590_340008200 ⚠ tRNA pseudouridine synthase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_004376 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_004376	Both
LTRL590_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007603	Both
LTRL590_260017200 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_002696	OG6
LTRL590_190007100 C-terminal motor kinesin, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006065	OG6

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