LTRL590_350038600

replication factor C, subunit 3, putative
Leishmania tropica L590 OG6: OG6_100321 OG7: OG7_0001167 128 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 128 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_210015900 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LTRL590_300033600 ⚠
Stabilization of polarity axis, putative
— OG7
LTRL590_300011300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350021500 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_340032500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330036200 ⚠
translation initiation factor IF-2, putative
— OG7
LTRL590_300010200 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_260017000 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_280032500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_240027900 ⚠
tubulin folding cofactor D, putative
— OG7
LTRL590_350051500 ⚠
sm-f snRNP core complex protein, putative
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_310026100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300013000 ⚠
heat shock protein grpe
— OG7
LTRL590_290032800 ⚠
protein kinase, putative
— OG7
LTRL590_340025100 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LTRL590_110005600 ⚠
protein kinase, putative
— OG7
LTRL590_080007400 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LTRL590_010012700 ⚠
ubiquitin activating enzyme, putative
— OG7
LTRL590_150018900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_080013200 ⚠
Beta-lactamase superfamily domain containing
— OG7
LTRL590_190014600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170016500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_280031500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_120010600 ⚠
WW domain containing protein, putative
— OG7
LTRL590_130010100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_030012300 ⚠
DEAD/DEAH box helicase, putative
— OG7
LTRL590_190011300 ⚠
Suppressor-of-White-APricot splicing regulato
— OG7
LTRL590_230008800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_230011600 ⚠
5'-3' exonuclease XRNC, putative
— OG7
LTRL590_090017700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_120007800 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
LTRL590_030009300 ⚠
TLD domain protein, conserved
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_200013900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_110016800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_080009500 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_150008300 ⚠
ecotin, putative
— OG7
LTRL590_150010200 ⚠
ecotin, putative
— OG7
LTRL590_150010100 ⚠
ecotin, putative
— OG7
LTRL590_360039400 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_220011500 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LTRL590_090022500 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.