LTRL590_120007800

cysteinyl-tRNA synthetase, putative

Leishmania tropica L590 OG6: OG6_100332 OG7: OG7_0003299 192 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 192 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG7 Tb927.4.2310 ↔ Tb927.6.950 OG7 LdBPK_120255.1 ↔ LdBPK_342110.1	OG7
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG7 Tb927.4.2310 ↔ Tb927.6.950 OG7 LdBPK_120255.1 ↔ LdBPK_342110.1	OG7
LTRL590_340027400 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG6 Tb927.4.2310 ↔ Tb927.6.950 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 +2 more	Both
LTRL590_300011300 hypothetical protein, conserved	—	OG6 LdBPK_120255.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_300580.1	Both
LTRL590_240027900 tubulin folding cofactor D, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006977	Both
LTRL590_230012300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_230660.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_230660.1	Both
LTRL590_360076300 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_230660.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_230660.1	Both
LTRL590_240005100 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 LdBPK_120255.1 ↔ LdBPK_240010.1 OG6 TCSYLVIO_001571 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977 +1 more	Both
LTRL590_340044700 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1	OG7
LTRL590_200008100 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_240010.1	Both
LTRL590_190014500 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_191010.1 OG6 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_191010.1	Both
LTRL590_350028800 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_230660.1	OG7
LTRL590_180017700 ⚠ bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
LTRL590_350019400 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_006977 ↔ TCSYLVIO_007511 OG6 Tb927.5.1090 ↔ Tb927.6.950 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007511 OG7 Tb927.5.1090 ↔ Tb927.6.950	Both
LTRL590_180017800 ⚠ Prolyl-tRNA synthetase, C-terminal, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
LTRL590_080009500 WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_120255.1 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_120255.1	Both
LTRL590_350054000 ⚠ Hsp70 protein, putative	—	OG7 TCSYLVIO_006278 ↔ TCSYLVIO_006977	OG7
LTRL590_320037000 ⚠ ubiquitin hydrolase, putative	—	OG6 TCSYLVIO_005374 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_006977	Both
LTRL590_120007200 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_006977	OG7
LTRL590_350029500 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_006977	OG7
LTRL590_270018700 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_006977	OG7
LTRL590_350049200 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007569	OG7
LTRL590_150017700 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007569	OG7
LTRL590_240014000 ⚠ inositol polyphosphate phosphatase, putative	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007569	OG7
LTRL590_000022000 hypothetical protein, conserved	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_008446	OG7
LTRL590_340019200 ⚠ inositol 5-phosphatase-like protein	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007569	OG7
LTRL590_010012700 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_010542	OG7
LTRL590_360017600 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_007569	OG7
LTRL590_330032300 ⚠ heat shock protein, putative	—	OG7 TCSYLVIO_006977 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_006977 ↔ TCSYLVIO_009151	OG7
LTRL590_360006700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_006977	OG7
LTRL590_070014500 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_006977	OG7
LTRL590_360048700 glycyl tRNA synthetase, putative	—	OG6 Tb927.11.9640 ↔ Tb927.6.950 OG7 Tb927.11.9640 ↔ Tb927.6.950	Both
LTRL590_150016600 glutamate dehydrogenase	—	OG6 Tb927.6.950 ↔ Tb927.9.5900 OG7 Tb927.6.950 ↔ Tb927.9.5900	Both
LTRL590_300013400 Armadillo/beta-catenin-like repeats, putative	—	OG6 TCSYLVIO_003145 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003145 ↔ TCSYLVIO_006977	Both
LTRL590_110016800 hypothetical protein, conserved	—	OG6 LdBPK_110930.1 ↔ LdBPK_120255.1 OG7 LdBPK_110930.1 ↔ LdBPK_120255.1	Both
LTRL590_300029000 SET domain containing protein, putative	—	OG6 Tb927.6.3610 ↔ Tb927.6.950 OG7 Tb927.6.3610 ↔ Tb927.6.950	Both
LTRL590_070017100 Domain of unknown function (DUF3437), putativ	—	OG6 LdBPK_071090.1 ↔ LdBPK_120255.1 OG7 LdBPK_071090.1 ↔ LdBPK_120255.1	Both
LTRL590_110016400 PUB domain containing protein, putative	—	OG6 LdBPK_110920.1 ↔ LdBPK_120255.1 OG7 LdBPK_110920.1 ↔ LdBPK_120255.1	Both
LTRL590_010011600 DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006977	Both
LTRL590_240026600 WD domain, G-beta repeat/PFU (PLAA family ubi	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_006977	Both
LTRL590_150008100 ribonucleoprotein p18, mitochondrial precurso	—	OG6 TCSYLVIO_002426 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_006977	Both
LTRL590_320007200 Histone chaperone Rttp106-like, putative	—	OG6 TCSYLVIO_006113 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_006977	Both
LTRL590_090012800 ubiquitin ligase, putative	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_006977	Both
LTRL590_350011700 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_006977	Both
LTRL590_190019800 ⚠ choline/Carnitine o-acyltransferase-like prot	—	OG7 Tb927.11.2230 ↔ Tb927.6.950	OG7
LTRL590_290020100 ⚠ carnitine/choline acetyltransferase, putative	—	OG7 Tb927.11.2230 ↔ Tb927.6.950	OG7
LTRL590_220008200 ⚠ carnitine palmitoyltransferase-like protein	—	OG7 Tb927.11.2230 ↔ Tb927.6.950	OG7
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_006977	OG7
LTRL590_360053300 paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006977	OG6
LTRL590_250030600 Leucine Rich repeats (2 copies), putative	—	OG6 TCSYLVIO_006421 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_006421 ↔ TCSYLVIO_006977	Both

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