LTRL590_010012700

ubiquitin activating enzyme, putative
Leishmania tropica L590 OG6: OG6_101845 OG7: OG7_0003569 126 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 126 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— OG7
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— OG7
LTRL590_300011300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_080009500 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_330026400 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LTRL590_000027600 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LTRL590_350013200 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LTRL590_110016400 ⚠
PUB domain containing protein, putative
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_090017700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350051500 ⚠
sm-f snRNP core complex protein, putative
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_300013000 ⚠
heat shock protein grpe
— OG7
LTRL590_290032800 ⚠
protein kinase, putative
— OG7
LTRL590_340049000 ⚠
nucleolar protein family a, putative
— OG7
LTRL590_270018700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_240026600 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LTRL590_320037000 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_340027400 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_350029500 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_120007200 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_360040400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350011700 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
LTRL590_320014900 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LTRL590_190014500 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LTRL590_090012800 ⚠
ubiquitin ligase, putative
— OG7
LTRL590_320007200 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LTRL590_000022000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_050006700 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LTRL590_010011600 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LTRL590_250022000 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LTRL590_210026900 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LTRL590_340023000 ⚠
Zeta toxin, putative
— OG7
LTRL590_000023500 ⚠
Exonuclease, putative
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_030009300 ⚠
TLD domain protein, conserved
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
LTRL590_100013800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_260024200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360064400 ⚠
adaptin, putative
— OG7
LTRL590_360081400 ⚠
beta-adaptin, putative
— OG7
LTRL590_360067800 ⚠
beta-adaptin protein, putative
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_290005200 ⚠
transcription factor-like protein
— OG7
LTRL590_240027900 ⚠
tubulin folding cofactor D, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.