LTRL590_300011300

hypothetical protein, conserved

Leishmania tropica L590 OG6: OG6_158251 OG7: OG7_0052285 205 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 205 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_010012700 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 LdBPK_080230.1 ↔ LdBPK_300580.1	OG7
LTRL590_080007400 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 LdBPK_080230.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 LdBPK_080230.1 ↔ LdBPK_300580.1	Both
LTRL590_110013400 ⚠ Cytosol aminopeptidase family, catalytic doma	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LTRL590_000006000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LTRL590_120007800 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_300580.1	Both
LTRL590_210016500 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	OG7
LTRL590_240027900 tubulin folding cofactor D, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003118 OG7 LdBPK_242100.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003118	Both
LTRL590_300010300 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	OG7
LTRL590_190014500 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_300580.1	Both
LTRL590_340027400 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_300580.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	Both
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	OG7
LTRL590_330026400 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_300580.1 ↔ LdBPK_332020.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 LdBPK_300580.1 ↔ LdBPK_332020.1	Both
LTRL590_080009500 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_300580.1	Both
LTRL590_000027600 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_300580.1 ↔ LdBPK_332020.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 LdBPK_300580.1 ↔ LdBPK_332020.1	Both
LTRL590_350029500 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005374	OG7
LTRL590_000022000 hypothetical protein, conserved	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008446	OG7
LTRL590_330032300 ⚠ heat shock protein, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009151	OG7
LTRL590_360067800 ⚠ beta-adaptin protein, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	OG7
LTRL590_270019500 hypothetical protein, conserved	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005512	OG7
LTRL590_110017300 ⚠ adaptin-related protein-like protein	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	OG7
LTRL590_270018700 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005374	OG7
LTRL590_360064400 ⚠ adaptin, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	OG7
LTRL590_350028800 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003118	OG7
LTRL590_360080800 ⚠ replication factor C, subunit 5, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_200016600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_170009800 ⚠ ATPase family associated with various cellula	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_350038600 ⚠ replication factor C, subunit 3, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_300032500 ⚠ replication factor C, subunit 2, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_270010700 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LTRL590_360006700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LTRL590_070014500 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LTRL590_030013500 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LTRL590_350061200 ⚠ SPRY domain/HECT-domain (ubiquitin-transferas	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LTRL590_300017100 ⚠ WW domain containing protein, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LTRL590_070008400 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LTRL590_210026900 ATP synthase F1 subunit gamma protein, putati	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009375	Both
LTRL590_340047000 GRIP domain containing protein, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003707 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003707	Both
LTRL590_230008300 pteridine reductase 1	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008848	Both
LTRL590_350017000 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008502	Both
LTRL590_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007603	Both
LTRL590_350019400 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007511	Both
LTRL590_190007100 C-terminal motor kinesin, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006065	OG6
LTRL590_360081400 ⚠ beta-adaptin, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_004597 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	Both
LTRL590_050006700 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009880	Both
LTRL590_000023500 Exonuclease, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010944	Both
LTRL590_350039800 hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005810	Both
LTRL590_070014900 ⚠ flavoprotein subunit-like protein	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008502	Both
LTRL590_110007200 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003118 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003118	Both
LTRL590_180015900 5-oxoprolinase, putative	—	OG6 LdBPK_181050.1 ↔ LdBPK_300580.1 OG7 LdBPK_181050.1 ↔ LdBPK_300580.1	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003118 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003118	Both

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