LTRL590_080007400

ubiquitin-activating enzyme-like protein
Leishmania tropica L590 OG6: OG6_101769 OG7: OG7_0003569 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_330026400 ⚠
Ribosome assembly protein rrb1, putative
— Both
LTRL590_200017700 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LTRL590_040009100 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— Both
LTRL590_000027600 ⚠
Ribosome assembly protein rrb1, putative
— Both
LTRL590_080009500 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_300011300 ⚠
hypothetical protein, conserved
— Both
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_290013400 ⚠
heat shock protein 90, putative
— +2 more Both
LTRL590_010011600 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LTRL590_240026600 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LTRL590_150008100 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LTRL590_320007200 ⚠
Histone chaperone Rttp106-like, putative
— Both
LTRL590_200008100 ⚠
developmentally regulated phosphoprotein-like
— Both
LTRL590_250022000 ⚠
Rab3 GTPase-activating protein catalytic subu
— Both
LTRL590_360040400 ⚠
hypothetical protein, conserved
— Both
LTRL590_230006100 ⚠
GDP-mannose pyrophosphorylase
— Both
LTRL590_090012800 ⚠
ubiquitin ligase, putative
— Both
LTRL590_240027900 ⚠
tubulin folding cofactor D, putative
— Both
LTRL590_230012300 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LTRL590_360076300 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LTRL590_100013800 ⚠
hypothetical protein, conserved
— Both
LTRL590_260024200 ⚠
hypothetical protein, conserved
— Both
LTRL590_250030600 ⚠
Leucine Rich repeats (2 copies), putative
— Both
LTRL590_350011700 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LTRL590_360053300
paraflagellar rod component, putative
— OG6
LTRL590_330034200 ⚠
aminopeptidase, putative
— OG7
LTRL590_030013500 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_070014500 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_360006700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LTRL590_350028800 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LTRL590_360017600 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LTRL590_240014000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LTRL590_150017700 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LTRL590_350049200 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LTRL590_340019200 ⚠
inositol 5-phosphatase-like protein
— OG7
LTRL590_250024200 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_340044700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_270018700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_350029500 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_120007200 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_000022000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_110017300 ⚠
adaptin-related protein-like protein
— OG7
LTRL590_360064400 ⚠
adaptin, putative
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.