LTRL590_330036200

translation initiation factor IF-2, putative
Leishmania tropica L590 OG6: OG6_101241 OG7: OG7_0005538 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_300032500 ⚠
replication factor C, subunit 2, putative
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_070008400 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LTRL590_000022400 ⚠
MORN repeat, putative
— OG7
LTRL590_260030600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LTRL590_340046400 ⚠
geranylgeranyltransferase, putative
— OG7
LTRL590_360080800 ⚠
replication factor C, subunit 5, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_330034200 ⚠
aminopeptidase, putative
— OG7
LTRL590_350033300
Short calmodulin-binding motif containing con
— Both
LTRL590_350054900
BRCA1 C Terminus (BRCT) domain containing pro
— Both
LTRL590_350038100
RNA-binding protein, putative
— Both
LTRL590_360020100
hypothetical protein, conserved
— Both
LTRL590_350022500
casein kinase II, putative
— OG6
LTRL590_340027400 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LTRL590_180015900
5-oxoprolinase, putative
— Both
LTRL590_280026200
p21-C-terminal region-binding protein, putati
— Both
LTRL590_290024100 ⚠
MORN repeat, putative
— Both
LTRL590_350049500 ⚠
predicted zinc finger protein
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_150008300 ⚠
ecotin, putative
— OG7
LTRL590_150010100 ⚠
ecotin, putative
— OG7
LTRL590_360039400 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_320013000 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_360060300 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_360077600 ⚠
protein transport protein Sec23-like protein
— OG7
LTRL590_310008100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_310008300 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LTRL590_350041200 ⚠
zinc finger protein, putative
— OG7
LTRL590_190013800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_080009500
WD domain, G-beta repeat, putative
— Both
LTRL590_260005500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_290011700 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LTRL590_280031500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_170016500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_170016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_270022500 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LTRL590_280032600 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LTRL590_190019100 ⚠
eukaryotic translation initiation factor-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.