LTRL590_350054900

BRCA1 C Terminus (BRCT) domain containing protein, putative

Leishmania tropica L590 OG6: OG6_146478 OG7: OG7_0043662 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_150012000 hypothetical protein, conserved	—	OG6 LdBPK_150690.1 ↔ LdBPK_354870.1 OG7 LdBPK_150690.1 ↔ LdBPK_354870.1	Both
LTRL590_180010800 hypothetical protein, conserved	—	OG6 LdBPK_180550.1 ↔ LdBPK_354870.1 OG7 LdBPK_180550.1 ↔ LdBPK_354870.1	Both
LTRL590_330009500 DNA mismatch repair protein MSH2, putative	—	OG6 LdBPK_330420.1 ↔ LdBPK_354870.1 OG7 LdBPK_330420.1 ↔ LdBPK_354870.1	Both
LTRL590_130010100 hypothetical protein, conserved	—	OG6 LdBPK_130510.1 ↔ LdBPK_354870.1 OG7 LdBPK_130510.1 ↔ LdBPK_354870.1	Both
LTRL590_080007400 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 LdBPK_080230.1 ↔ LdBPK_354870.1 OG7 LdBPK_080230.1 ↔ LdBPK_354870.1	Both
LTRL590_220011500 guide RNA associated protein, GAP2, putative	—	OG6 LdBPK_220520.1 ↔ LdBPK_354870.1 OG7 LdBPK_220520.1 ↔ LdBPK_354870.1	Both
LTRL590_210015900 Domain of unknown function (DUF4042)/HEAT-lik	—	OG6 LdBPK_211060.1 ↔ LdBPK_354870.1 OG7 LdBPK_211060.1 ↔ LdBPK_354870.1	Both
LTRL590_000023900 ⚠ protein transport protein SEC23, putative	—	OG6 LdBPK_100330.1 ↔ LdBPK_354870.1 OG7 LdBPK_100330.1 ↔ LdBPK_354870.1	Both
LTRL590_120007800 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_354870.1 OG7 LdBPK_120255.1 ↔ LdBPK_354870.1	Both
LTRL590_320016900 hypothetical protein, conserved	—	OG6 LdBPK_321100.1 ↔ LdBPK_354870.1 OG7 LdBPK_321100.1 ↔ LdBPK_354870.1	Both
LTRL590_260019700 ⚠ farnesyltransferase beta subunit	—	OG6 LdBPK_261450.1 ↔ LdBPK_354870.1 OG7 LdBPK_261450.1 ↔ LdBPK_354870.1	Both
LTRL590_240027900 tubulin folding cofactor D, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_354870.1 OG7 LdBPK_242100.1 ↔ LdBPK_354870.1	Both
LTRL590_150010200 ⚠ ecotin, putative	—	OG6 LdBPK_150540.1 ↔ LdBPK_354870.1 OG7 LdBPK_150540.1 ↔ LdBPK_354870.1	Both
LTRL590_030009300 ⚠ TLD domain protein, conserved	—	OG6 LdBPK_030430.1 ↔ LdBPK_354870.1 OG7 LdBPK_030430.1 ↔ LdBPK_354870.1	Both
LTRL590_260017000 ⚠ Leucine rich repeat, putative	—	OG6 LdBPK_261200.1 ↔ LdBPK_354870.1 OG7 LdBPK_261200.1 ↔ LdBPK_354870.1	Both
LTRL590_320017400 ⚠ HECT-domain (ubiquitin-transferase), putative	—	OG6 LdBPK_321150.1 ↔ LdBPK_354870.1 OG7 LdBPK_321150.1 ↔ LdBPK_354870.1	Both
LTRL590_160018500 ⚠ WW domain containing protein, putative	—	OG6 LdBPK_161180.1 ↔ LdBPK_354870.1 OG7 LdBPK_300970.1 ↔ LdBPK_354870.1 OG7 LdBPK_161180.1 ↔ LdBPK_354870.1	Both
LTRL590_300011300 hypothetical protein, conserved	—	OG6 LdBPK_300580.1 ↔ LdBPK_354870.1 OG7 LdBPK_300580.1 ↔ LdBPK_354870.1	Both
LTRL590_180018300 hypothetical protein, conserved	—	OG6 LdBPK_181300.1 ↔ LdBPK_354870.1 OG7 LdBPK_181300.1 ↔ LdBPK_354870.1	Both
LTRL590_300015300 ⚠ ubiquitin-protein ligase, putative	—	OG6 LdBPK_300970.1 ↔ LdBPK_354870.1 OG7 LdBPK_300970.1 ↔ LdBPK_354870.1 OG7 LdBPK_161180.1 ↔ LdBPK_354870.1	Both
LTRL590_290031300 aspartyl aminopeptidase, putative	—	OG6 LdBPK_292470.1 ↔ LdBPK_354870.1 OG7 LdBPK_292470.1 ↔ LdBPK_354870.1	Both
LTRL590_260016600 hypothetical protein, conserved	—	OG6 LdBPK_261160.1 ↔ LdBPK_354870.1 OG7 LdBPK_261160.1 ↔ LdBPK_354870.1	Both
LTRL590_240015700 ⚠ replication factor C, subunit 1, putative	—	OG6 LdBPK_241010.1 ↔ LdBPK_354870.1 OG7 LdBPK_241010.1 ↔ LdBPK_354870.1	Both
LTRL590_090017700 hypothetical protein, conserved	—	OG6 LdBPK_091160.1 ↔ LdBPK_354870.1 OG7 LdBPK_091160.1 ↔ LdBPK_354870.1	Both
LTRL590_290032800 protein kinase, putative	—	OG6 LdBPK_292600.1 ↔ LdBPK_354870.1 OG7 LdBPK_292600.1 ↔ LdBPK_354870.1	Both
LTRL590_350033300 Short calmodulin-binding motif containing con	—	OG6 LdBPK_352820.1 ↔ LdBPK_354870.1 OG7 LdBPK_352820.1 ↔ LdBPK_354870.1	Both
LTRL590_230008800 hypothetical protein, conserved	—	OG6 LdBPK_230360.1 ↔ LdBPK_354870.1 OG7 LdBPK_230360.1 ↔ LdBPK_354870.1	Both
LTRL590_350026100 kinesin, putative	—	OG6 Tb927.9.15470 ↔ Tb927.9.9730 OG7 Tb927.9.15470 ↔ Tb927.9.9730	Both
LTRL590_350014100 hypothetical protein, conserved	—	OG6 LdBPK_350940.1 ↔ LdBPK_354870.1 OG7 LdBPK_350940.1 ↔ LdBPK_354870.1	Both
LTRL590_260017600 hypothetical protein, conserved	—	OG6 LdBPK_261260.1 ↔ LdBPK_354870.1 OG7 LdBPK_261260.1 ↔ LdBPK_354870.1	Both
LTRL590_030012300 ⚠ DEAD/DEAH box helicase, putative	—	OG6 LdBPK_030670.1 ↔ LdBPK_354870.1 OG7 LdBPK_030670.1 ↔ LdBPK_354870.1	Both
LTRL590_020006200 Ankyrin repeats (3 copies)/Zinc finger, C3HC4	—	OG6 LdBPK_020120.1 ↔ LdBPK_354870.1 OG7 LdBPK_020120.1 ↔ LdBPK_354870.1	Both
LTRL590_230011600 5'-3' exonuclease XRNC, putative	—	OG6 LdBPK_230600.1 ↔ LdBPK_354870.1 OG7 LdBPK_230600.1 ↔ LdBPK_354870.1	Both
LTRL590_110016800 hypothetical protein, conserved	—	OG6 LdBPK_110930.1 ↔ LdBPK_354870.1 OG7 LdBPK_110930.1 ↔ LdBPK_354870.1	Both
LTRL590_190014500 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_354870.1 OG7 LdBPK_191010.1 ↔ LdBPK_354870.1	Both
LTRL590_340027400 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_342110.1 ↔ LdBPK_354870.1 OG7 LdBPK_342110.1 ↔ LdBPK_354870.1	Both
LTRL590_300010200 ⚠ eukaryotic translation initiation factor 4e,	—	OG6 LdBPK_300460.1 ↔ LdBPK_354870.1 OG7 LdBPK_300460.1 ↔ LdBPK_354870.1	Both
LTRL590_350038100 RNA-binding protein, putative	—	OG6 LdBPK_353250.1 ↔ LdBPK_354870.1 OG7 LdBPK_353250.1 ↔ LdBPK_354870.1	Both
LTRL590_180017700 ⚠ bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 LdBPK_181220.1 ↔ LdBPK_354870.1 OG6 LdBPK_181230.1 ↔ LdBPK_354870.1 OG7 LdBPK_181220.1 ↔ LdBPK_354870.1 OG7 LdBPK_181230.1 ↔ LdBPK_354870.1	Both
LTRL590_180017800 ⚠ Prolyl-tRNA synthetase, C-terminal, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_354870.1 OG6 LdBPK_181230.1 ↔ LdBPK_354870.1 OG7 LdBPK_181220.1 ↔ LdBPK_354870.1 OG7 LdBPK_181230.1 ↔ LdBPK_354870.1	Both
LTRL590_340032500 hypothetical protein, conserved	—	OG6 LdBPK_342590.1 ↔ LdBPK_354870.1 OG7 LdBPK_342590.1 ↔ LdBPK_354870.1	Both
LTRL590_250031800 hypothetical protein, conserved	—	OG6 Tb927.3.2490 ↔ Tb927.9.9730 OG7 Tb927.3.2490 ↔ Tb927.9.9730	Both
LTRL590_330026400 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_332020.1 ↔ LdBPK_354870.1 OG7 LdBPK_332020.1 ↔ LdBPK_354870.1	Both
LTRL590_000027600 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_332020.1 ↔ LdBPK_354870.1 OG7 LdBPK_332020.1 ↔ LdBPK_354870.1	Both
LTRL590_070017100 Domain of unknown function (DUF3437), putativ	—	OG6 LdBPK_071090.1 ↔ LdBPK_354870.1 OG7 LdBPK_071090.1 ↔ LdBPK_354870.1	Both
LTRL590_110016400 PUB domain containing protein, putative	—	OG6 LdBPK_110920.1 ↔ LdBPK_354870.1 OG7 LdBPK_110920.1 ↔ LdBPK_354870.1	Both
LTRL590_330033000 hypothetical protein, conserved	—	OG6 LdBPK_332590.1 ↔ LdBPK_354870.1 OG7 LdBPK_332590.1 ↔ LdBPK_354870.1	Both
LTRL590_220005600 ⚠ transcription factor-like protein	—	OG6 LdBPK_220007.1 ↔ LdBPK_354870.1 OG7 LdBPK_220007.1 ↔ LdBPK_354870.1	Both
LTRL590_110016100 Leucine Rich repeat, putative	—	OG6 LdBPK_110890.1 ↔ LdBPK_354870.1 OG7 LdBPK_110890.1 ↔ LdBPK_354870.1	Both
LTRL590_360060700 Calponin homology (CH) domain containing prot	—	OG6 LdBPK_354870.1 ↔ LdBPK_365150.1 OG7 LdBPK_354870.1 ↔ LdBPK_365150.1	Both

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