LTRL590_320016900

hypothetical protein, conserved
Leishmania tropica L590 OG6: OG6_199990 OG7: OG7_0084103 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
LTRL590_110016100
Leucine Rich repeat, putative
— Both
LTRL590_310015100 ⚠
ras-like small GTPases, putative
— OG6
LTRL590_310014900 ⚠
ras-like small GTPases, putative
— OG6
LTRL590_190014600
hypothetical protein, conserved
— Both
LTRL590_080009500
WD domain, G-beta repeat, putative
— Both
LTRL590_300013000 ⚠
heat shock protein grpe
— Both
LTRL590_340046400 ⚠
geranylgeranyltransferase, putative
— OG7
LTRL590_070008400 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_160018500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_300032500 ⚠
replication factor C, subunit 2, putative
— OG7
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_110016400
PUB domain containing protein, putative
— Both
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360080800 ⚠
replication factor C, subunit 5, putative
— OG7
LTRL590_300012900 ⚠
co-chaperone GrpE, putative
— OG7
LTRL590_250024200 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_010012700 ⚠
ubiquitin activating enzyme, putative
— OG7
LTRL590_350051500 ⚠
sm-f snRNP core complex protein, putative
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_010006500 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_300018400 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LTRL590_360054700 ⚠
ubiquitin protein ligase, putative
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
LTRL590_260019700 ⚠
farnesyltransferase beta subunit
— Both
LTRL590_080007400 ⚠
ubiquitin-activating enzyme-like protein
— Both
LTRL590_220011500
guide RNA associated protein, GAP2, putative
— Both
LTRL590_210015900
Domain of unknown function (DUF4042)/HEAT-lik
— Both
LTRL590_330026400 ⚠
Ribosome assembly protein rrb1, putative
— Both
LTRL590_350014100
hypothetical protein, conserved
— Both
LTRL590_330009500
DNA mismatch repair protein MSH2, putative
— Both
LTRL590_000027600 ⚠
Ribosome assembly protein rrb1, putative
— Both
LTRL590_350038100
RNA-binding protein, putative
— Both
LTRL590_320017400 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LTRL590_330030900
glycosyl hydrolase-like protein
— Both
LTRL590_350054900
BRCA1 C Terminus (BRCT) domain containing pro
— Both
LTRL590_350033300
Short calmodulin-binding motif containing con
— Both
LTRL590_360060700
Calponin homology (CH) domain containing prot
— Both
LTRL590_340032500
hypothetical protein, conserved
— Both
LTRL590_180010800
hypothetical protein, conserved
— Both
LTRL590_030009300 ⚠
TLD domain protein, conserved
— Both
LTRL590_300011300
hypothetical protein, conserved
— Both
LTRL590_180018300
hypothetical protein, conserved
— Both
LTRL590_300015300 ⚠
ubiquitin-protein ligase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.