LTRL590_360054700

ubiquitin protein ligase, putative
Leishmania tropica L590 OG6: OG6_478893 OG7: OG7_0002947 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_320031200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_250024200 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_080007400 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LTRL590_340023300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_010012700 ⚠
ubiquitin activating enzyme, putative
— OG7
LTRL590_350051500 ⚠
sm-f snRNP core complex protein, putative
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_260012200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_010006500 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_260012100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_300018400 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LTRL590_310041000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_110010100 ⚠
chromatin binding protein, putative
— OG7
LTRL590_170006800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360051400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360034600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LTRL590_150018900 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_340046700 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_350022600 ⚠
ubiquitin hydrolase, putative
— OG7
LTRL590_050014400 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LTRL590_280025100 ⚠
replication factor A, 51kDa subunit, putative
— OG7
LTRL590_280027600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_230013500 ⚠
Galactose oxidase, central domain containing
— OG7
LTRL590_160009300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LTRL590_190014600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_270015000 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LTRL590_150016600 ⚠
glutamate dehydrogenase
— OG7
LTRL590_340049600 ⚠
sjogren s syndrome nuclear autoantigen 1, put
— OG7
LTRL590_340032400 ⚠
methyltransferase-like protein
— OG7
LTRL590_210015900 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LTRL590_180012000 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LTRL590_070006100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LTRL590_110016400 ⚠
PUB domain containing protein, putative
— OG7
LTRL590_220011500 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LTRL590_050010500 ⚠
Surp module, putative
— OG7
LTRL590_180010800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330039100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330026400 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LTRL590_350014100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330009500 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LTRL590_000027600 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LTRL590_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_110006600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_290032800 ⚠
protein kinase, putative
— OG7
LTRL590_290019100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300015900 ⚠
p22 protein precursor, putative
— OG7
LTRL590_300036500 ⚠
calmodulin-related protein, putative
— OG7
LTRL590_080009500 ⚠
WD domain, G-beta repeat, putative
— OG7
LTRL590_030009300 ⚠
TLD domain protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.