LTRL590_210015900

Domain of unknown function (DUF4042)/HEAT-like repeat, putative
Leishmania tropica L590 OG6: OG6_158058 OG7: OG7_0008375 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_260016600
hypothetical protein, conserved
— Both
LTRL590_340032500
hypothetical protein, conserved
— Both
LTRL590_350061200 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LTRL590_020006200
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— Both
LTRL590_350060500
isopentenyl-diphosphate delta-isomerase (type
— Both
LTRL590_070011600
hypothetical protein, conserved
— Both
LTRL590_180017700 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LTRL590_180017800 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— Both
LTRL590_110016400
PUB domain containing protein, putative
— Both
LTRL590_110016100
Leucine Rich repeat, putative
— Both
LTRL590_300021100 ⚠
pseudouridine synthase A-like protein, putati
— Both
LTRL590_190014600
hypothetical protein, conserved
— Both
LTRL590_080009500
WD domain, G-beta repeat, putative
— Both
LTRL590_180015900
5-oxoprolinase, putative
— Both
LTRL590_330034200 ⚠
aminopeptidase, putative
— OG7
LTRL590_260007700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_360006700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LTRL590_010012700 ⚠
ubiquitin activating enzyme, putative
— OG7
LTRL590_250005400 ⚠
beta-galactofuranosyltransferase-like protein
— OG7
LTRL590_260010200 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LTRL590_190014300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LTRL590_340008200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LTRL590_260008800 ⚠
pseudouridylate synthase-like protein
— OG7
LTRL590_250024200 ⚠
LSM domain containing protein, putative
— OG7
LTRL590_290011700 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_070008400 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_300017100 ⚠
WW domain containing protein, putative
— OG7
LTRL590_310008300 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_360026500 ⚠
TLD, putative
— OG7
LTRL590_060014800 ⚠
TLD, putative
— OG7
LTRL590_360039400 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_350041200 ⚠
zinc finger protein, putative
— OG7
LTRL590_190013800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350049500 ⚠
predicted zinc finger protein
— OG7
LTRL590_260005500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350029900 ⚠
ubiquitin-protein ligase, putative
— OG7
LTRL590_320017200 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_350051500 ⚠
sm-f snRNP core complex protein, putative
— OG7
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_260030600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LTRL590_340046400 ⚠
geranylgeranyltransferase, putative
— OG7
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.