LTRL590_280032600

eukaryotic translation initiation factor 4e, putative
Leishmania tropica L590 OG6: OG6_134811 OG7: OG7_0002303 207 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 207 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_280026200 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LTRL590_180005200 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LTRL590_210007000 ⚠
serine/threonine-protein kinase-like protein
— OG7
LTRL590_280027500 ⚠
protein kinase, putative
— OG7
LTRL590_360014800 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LTRL590_350005200 ⚠
pyruvate kinase
— OG7
LTRL590_160011000 ⚠
dihydroorotase, putative
— OG7
LTRL590_310017000 ⚠
biotin/lipoate protein ligase-like protein
— OG7
LTRL590_280026600 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LTRL590_290027300 ⚠
serine/threonine protein kinase, putative
— OG7
LTRL590_360045700 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LTRL590_290009000 ⚠
UBX domain-containing protein
— OG7
LTRL590_360014900 ⚠
SNF1-related protein kinases, putative
— OG7
LTRL590_210005600 ⚠
BAR domain containing protein, putative
— OG7
LTRL590_320031900 ⚠
Cid1 family poly A polymerase, putative
— OG7
LTRL590_260033100 ⚠
6-phosphogluconolactonase
— OG7
LTRL590_210012200 ⚠
phosphoglucomutase, putative
— OG7
LTRL590_000009900 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LTRL590_180007400 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
LTRL590_120005200 ⚠
PITH domain containing protein, putative
— OG7
LTRL590_250027500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_080010200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_000023700 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LTRL590_360011100 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LTRL590_240009000 ⚠
aspartate aminotransferase, putative
— OG7
LTRL590_310024900 ⚠
diphthine synthase-like protein
— OG7
LTRL590_110016400 ⚠
PUB domain containing protein, putative
— OG7
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— OG7
LTRL590_290031300 ⚠
aspartyl aminopeptidase, putative
— OG7
LTRL590_360056000 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LTRL590_160022600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_220006100 ⚠
glutamine amidotransferase, putative
— OG7
LTRL590_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LTRL590_290011700 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LTRL590_290028200 ⚠
conserved hypothetical protein, putative
— OG7
LTRL590_220005600 ⚠
transcription factor-like protein
— OG7
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— OG7
LTRL590_260024300 ⚠
deoxyhypusine hydroxylase, putative
— OG7
LTRL590_150012000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_220014700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LTRL590_320013000 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_260017000 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_360060300 ⚠
Leucine rich repeat, putative
— OG7
LTRL590_190014500 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LTRL590_070017100 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LTRL590_330015700 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LTRL590_030010900 ⚠
quinone oxidoreductase, putative
— OG7
LTRL590_290008100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_160020400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350048500 ⚠
Protein of unknown function (DUF2009), putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.