LTRL590_270022500

eukaryotic translation initiation factor eIF-4E, putative
Leishmania tropica L590 OG6: OG6_100627 OG7: OG7_0002303 220 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 220 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_000016900 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LTRL590_280020000 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_120010600 ⚠
WW domain containing protein, putative
— OG7
LTRL590_280031500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_170016500 ⚠
WW domain containing protein, putative
— OG7
LTRL590_170016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_280019800 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LTRL590_280019700 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LTRL590_280019900 ⚠
hypothetical protein
— OG7
LTRL590_020006300 ⚠
Vps51/Vps67, putative
— OG7
LTRL590_190019800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LTRL590_220008200 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LTRL590_340045800 ⚠
adaptor gamma-1 chain, putative
— OG7
LTRL590_340022200 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LTRL590_330036600 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_340008900 ⚠
Conserved oligomeric complex COG6, putative
— OG7
LTRL590_230027000 ⚠
neutral sphingomyelinase activation associate
— OG7
LTRL590_320024600 ⚠
Phosphatidylethanolamine-binding protein, put
— OG7
LTRL590_330036200 ⚠
translation initiation factor IF-2, putative
— OG7
LTRL590_300011300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_320016300 ⚠
Vps23 core domain containing protein, putativ
— OG7
LTRL590_330033000 ⚠
hypothetical protein, conserved
— OG7
LTRL590_350054900 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LTRL590_000028000 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LTRL590_360013300 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360024100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360064800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360024000 ⚠
neurobeachin/beige protein, putative
— OG7
LTRL590_200016600 ⚠
hypothetical protein, conserved
— OG7
LTRL590_030013500 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_260007700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_070014500 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LTRL590_360006700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LTRL590_130008300 ⚠
Alba, putative
— OG7
LTRL590_130008200 ⚠
hypothetical protein
— OG7
LTRL590_270010700 ⚠
replication factor C, subunit 4, putative
— OG7
LTRL590_080012800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_180017700 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LTRL590_300032500 ⚠
replication factor C, subunit 2, putative
— OG7
LTRL590_350038600 ⚠
replication factor C, subunit 3, putative
— OG7
LTRL590_180017800 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— OG7
LTRL590_170009800 ⚠
ATPase family associated with various cellula
— OG7
LTRL590_310042600 ⚠
aldehyde reductase, putative
— OG7
LTRL590_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_340027400 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LTRL590_070005600 ⚠
alpha-adaptin-like protein
— OG7
LTRL590_240027900 ⚠
tubulin folding cofactor D, putative
— OG7
LTRL590_150009400 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.