LTRL590_140021300

inositol-3-phosphate synthase

Leishmania tropica L590 OG6: OG6_100830 OG7: OG7_0006574 188 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 188 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_110017400 pyruvate phosphate dikinase, putative	—	OG6 LdBPK_111000.1 ↔ LdBPK_141450.1 OG6 Tb927.10.7110 ↔ Tb927.11.6280 OG7 Tb927.10.7110 ↔ Tb927.11.6280 OG7 LdBPK_111000.1 ↔ LdBPK_141450.1	Both
LTRL590_040008100 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	OG7
LTRL590_280008300 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	Both
LTRL590_030006400 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	OG7
LTRL590_250014900 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_007401 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LTRL590_190012800 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LTRL590_230006100 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LTRL590_280009400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 +1 more	Both
LTRL590_330009000 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG6 LdBPK_141450.1 ↔ LdBPK_330340.1 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LTRL590_330021400 ⚠ protein kinase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LTRL590_350052400 Cysteine-rich motif following a subset of SET	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LTRL590_250016800 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_251070.1 OG7 LdBPK_141450.1 ↔ LdBPK_251070.1	Both
LTRL590_300037800 ⚠ glutamyl-tRNA synthetase, putative	—	OG7 Tb927.10.7110 ↔ Tb927.9.5210	OG7
LTRL590_290027800 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_141450.1	OG7
LTRL590_110007200 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LTRL590_030014700 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LTRL590_320048000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007453	Both
LTRL590_120008100 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_141450.1 OG7 LdBPK_120105.1 ↔ LdBPK_141450.1	Both
LTRL590_220019900 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007453	Both
LTRL590_250007300 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	Both
LTRL590_360005600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LTRL590_270031400 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LTRL590_360068100 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LTRL590_050012700 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007453	Both
LTRL590_290033300 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LTRL590_360029500 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LTRL590_220016400 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LTRL590_290028300 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007453	Both
LTRL590_350009100 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007453	Both
LTRL590_360037400 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LTRL590_310022300 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_311440.1 OG7 LdBPK_141450.1 ↔ LdBPK_311440.1	Both
LTRL590_260016400 ⚠ RNA pseudouridylate synthase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_261140.1 OG7 LdBPK_141450.1 ↔ LdBPK_261140.1	Both
LTRL590_350012300 proteasome activator protein pa26, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_350770.1 OG7 LdBPK_141450.1 ↔ LdBPK_350770.1	Both
LTRL590_290019700 Heat shock protein 100 kDa	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LTRL590_240006300 ankyrin/TPR repeat protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_240130.1	OG6
LTRL590_150012000 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_150690.1 OG7 LdBPK_141450.1 ↔ LdBPK_150690.1	Both
LTRL590_170014600 Phosphorylated CTD interacting factor 1 WW do	—	OG6 LdBPK_141450.1 ↔ LdBPK_171050.1 OG7 LdBPK_141450.1 ↔ LdBPK_171050.1	Both
LTRL590_230018900 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_231180.1 OG7 LdBPK_141450.1 ↔ LdBPK_231180.1	Both
LTRL590_000028900 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LTRL590_350028100 ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_352320.1	OG6
LTRL590_300020100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LTRL590_000028800 ⚠ Peptidase dimerisation domain/Peptidase famil	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LTRL590_330034200 ⚠ aminopeptidase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_141450.1 OG7 LdBPK_110640.1 ↔ LdBPK_141450.1 OG7 LdBPK_141450.1 ↔ LdBPK_332700.1	Both
LTRL590_340039200 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	OG7
LTRL590_300010400 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_300480.1 OG7 LdBPK_141450.1 ↔ LdBPK_300480.1	Both
LTRL590_300025800 calpain-like cysteine peptidase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_302040.1	OG6
LTRL590_340046700 ⚠ ubiquitin hydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_343890.1 OG7 LdBPK_141450.1 ↔ LdBPK_343890.1	Both
LTRL590_360074900 flagellum transition zone component, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_366480.1 OG7 LdBPK_141450.1 ↔ LdBPK_366480.1	Both
LTRL590_360067700 CAP/Srv2p, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_365830.1 OG7 LdBPK_141450.1 ↔ LdBPK_365830.1	Both
LTRL590_290019400 ⚠ Hsp70 protein/TPR repeat, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_291330.1 OG7 LdBPK_141450.1 ↔ LdBPK_291330.1	Both

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