LTRL590_220016400

translation initiation factor IF-2, putative
Leishmania tropica L590 OG6: OG6_100987 OG7: OG7_0005015 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_240017900 ⚠
hypothetical protein, conserved
— Both
LTRL590_220006500 ⚠
hypothetical protein, conserved
— Both
LTRL590_110012300 ⚠
hypothetical protein, conserved
— Both
LTRL590_220008100 ⚠
hypothetical protein, conserved
— Both
LTRL590_240008000 ⚠
hypothetical protein, conserved
— Both
LTRL590_180005000 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LTRL590_350032900 ⚠
acyl-CoA dehydrogenase, putative
— Both
LTRL590_340027400 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LTRL590_170007900 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LTRL590_270008800 ⚠
nucleoporin, putative
— Both
LTRL590_350008600 ⚠
hypothetical protein, conserved
— Both
LTRL590_270031400 ⚠
TPR-repeat protein, putative
— OG6
LTRL590_300017400 ⚠
importin alpha, putative
— Both
LTRL590_310039000 ⚠
calreticulin, putative
— Both
LTRL590_260014700 ⚠
Glucosidase II beta subunit-like/Glucosidase
— Both
LTRL590_000028400 ⚠
calreticulin, putative
— Both
LTRL590_360029500 ⚠
NOL1/NOP2/sun family, putative
— Both
LTRL590_360068100 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LTRL590_280009400 ⚠
DIS3-like exonuclease, putative
— Both
LTRL590_300037200 ⚠
UV excision repair RAD23-like protein
— Both
LTRL590_360032500 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— Both
LTRL590_210014200 ⚠
methionyl-tRNA synthetase
— Both
LTRL590_350009100 ⚠
hypothetical protein, conserved
— Both
LTRL590_310044000 ⚠
Component of IIS longevity pathway SMK-1, put
— Both
LTRL590_310043800 ⚠
hypothetical protein, conserved
— Both
LTRL590_050012700 ⚠
hypothetical protein, conserved
— Both
LTRL590_000007200 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LTRL590_140021300 ⚠
inositol-3-phosphate synthase
— Both
LTRL590_290028300 ⚠
UDP-glucose:Glycoprotein Glucosyltransferase,
— Both
LTRL590_360005600 ⚠
stress-inducible protein STI1 homolog
— OG6
LTRL590_140010200 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LTRL590_250014900 ⚠
protein kinase, putative
— Both
LTRL590_200017200 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LTRL590_300035400 ⚠
DNA ligase I, putative
— Both
LTRL590_290022700 ⚠
XPC-binding domain/UBA/TS-N domain containing
— Both
LTRL590_340008500 ⚠
deoxyhypusine synthase
— Both
LTRL590_290005600 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LTRL590_290033300 ⚠
NOL1/NOP2/sun family, putative
— Both
LTRL590_130015300 ⚠
leucyl-tRNA synthetase, putative
— Both
LTRL590_060014200 ⚠
acyl-coenzyme a dehydrogenase, putative
— Both
LTRL590_350057800 ⚠
hypothetical protein, conserved
— Both
LTRL590_340026200 ⚠
Endonuclease/Exonuclease/phosphatase family,
— Both
LTRL590_350015600
protein kinase, putative
— OG6
LTRL590_250007300 ⚠
cleavage and polyadenylation specificity fact
— Both
LTRL590_230006100 ⚠
GDP-mannose pyrophosphorylase
— Both
LTRL590_250031800 ⚠
hypothetical protein, conserved
— Both
LTRL590_190012800 ⚠
ABC transport system ATP-binding protein, put
— Both
LTRL590_280034900 ⚠
Uncharacterized ACR, COG1678, putative
— Both
LTRL590_360073200 ⚠
disgorgin, putative
— Both
LTRL590_300029000 ⚠
SET domain containing protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.