LTRL590_300035400

DNA ligase I, putative
Leishmania tropica L590 OG6: OG6_100906 OG7: OG7_0002598 159 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 159 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_030013200 ⚠
Leucine rich repeat/Ubiquitin-like domain con
— Both
LTRL590_310029500 ⚠
dihydrouridine synthase (Dus), putative
— Both
LTRL590_000019000 ⚠
dihydrouridine synthase (Dus), putative
— Both
LTRL590_340018100 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LTRL590_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LTRL590_170007900 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LTRL590_080008300 ⚠
Isochorismatase family, putative
— OG7
LTRL590_090007800 ⚠
hypothetical protein, conserved
— Both
LTRL590_280031200 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LTRL590_250028600 ⚠
hypothetical protein, conserved
— Both
LTRL590_340043100 ⚠
hypothetical protein, conserved
— Both
LTRL590_360006500 ⚠
PUB domain containing protein, putative
— Both
LTRL590_350039900 ⚠
Poly A polymerase regulatory subunit, putativ
— Both
LTRL590_340019900 ⚠
hypothetical protein, conserved
— Both
LTRL590_200007700 ⚠
deoxyhypusine synthase, putative
— Both
LTRL590_140020800 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LTRL590_300037200 ⚠
UV excision repair RAD23-like protein
— Both
LTRL590_180005000 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LTRL590_300039300 ⚠
S-adenosylmethionine decarboxylase
— Both
LTRL590_270014200 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_280022600 ⚠
phosphonopyruvate decarboxylase-like protein
— Both
LTRL590_220016400 ⚠
translation initiation factor IF-2, putative
— Both
LTRL590_050012700 ⚠
hypothetical protein, conserved
— Both
LTRL590_020008600
casein kinase II, alpha chain, putative
— OG6
LTRL590_230025800 ⚠
hypothetical protein, conserved
— Both
LTRL590_220019900 ⚠
alanyl-tRNA synthetase, putative
— Both
LTRL590_280009400 ⚠
DIS3-like exonuclease, putative
— Both
LTRL590_210017000 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LTRL590_280025100 ⚠
replication factor A, 51kDa subunit, putative
— Both
LTRL590_000020200 ⚠
Metallo-beta-lactamase superfamily, putative
— Both
LTRL590_220015400 ⚠
hypothetical protein, conserved
— Both
LTRL590_220015300 ⚠
Beta-lactamase superfamily domain containing
— Both
LTRL590_000020100 ⚠
hypothetical protein
— Both
LTRL590_320048000 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LTRL590_030012900 ⚠
TatD related DNase, putative
— Both
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— Both
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_040008100 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LTRL590_280008300 ⚠
rrp44p homologue, putative
— OG7
LTRL590_100006400 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LTRL590_260026200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_120005700 ⚠
ribonuclease mar1
— OG7
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_300012500 ⚠
nuclear movement protein, putative
— OG7
LTRL590_350041500 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LTRL590_330021400 ⚠
protein kinase, putative
— OG7
LTRL590_340039200 ⚠
cleavage and polyadenylation specificity fact
— OG7
LTRL590_180016600 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LTRL590_330009000 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LTRL590_170016400 ⚠
NOL1/NOP2/sun family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.