LTRL590_310029500

dihydrouridine synthase (Dus), putative
Leishmania tropica L590 OG6: OG6_101867 OG7: OG7_0002064 216 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 216 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_300035400 ⚠
DNA ligase I, putative
— Both
LTRL590_290026700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_290008000 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LTRL590_350052400 ⚠
Cysteine-rich motif following a subset of SET
— OG7
LTRL590_180006000 ⚠
alpha glucosidase II subunit, putative
— OG7
LTRL590_310043800 ⚠
hypothetical protein, conserved
— OG7
LTRL590_310044000 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
LTRL590_360051800 ⚠
glycosyl hydrolase-like protein
— OG7
LTRL590_240017900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— OG7
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— OG7
LTRL590_220008100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_300012000 ⚠
histidyl-tRNA synthetase, putative
— OG7
LTRL590_330021400 ⚠
protein kinase, putative
— OG7
LTRL590_250014900 ⚠
protein kinase, putative
— OG7
LTRL590_300034700 ⚠
GTPase activator-like protein
— OG7
LTRL590_000007200 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LTRL590_170020400 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LTRL590_360068100 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_160009300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_340027400 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LTRL590_300017400 ⚠
importin alpha, putative
— OG7
LTRL590_180012100 ⚠
HEAT repeat, putative
— OG7
LTRL590_360073200 ⚠
disgorgin, putative
— OG7
LTRL590_360073300 ⚠
rab-like GTPase activating protein, putative
— OG7
LTRL590_000028400 ⚠
calreticulin, putative
— OG7
LTRL590_350057500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360054700 ⚠
ubiquitin protein ligase, putative
— OG7
LTRL590_360051400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_360034600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LTRL590_300028500 ⚠
Leucine-rich repeats, bacterial type, putativ
— OG7
LTRL590_340045700 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LTRL590_310041000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LTRL590_230008700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LTRL590_350059100 ⚠
GTP-binding protein, putative
— OG7
LTRL590_050009100 ⚠
GTPase, putative
— OG7
LTRL590_330032400 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_200017200 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
LTRL590_260026200 ⚠
hypothetical protein, conserved
— OG7
LTRL590_080008300 ⚠
Isochorismatase family, putative
— OG7
LTRL590_070008400 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LTRL590_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_180009000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LTRL590_270032400 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LTRL590_110009900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LTRL590_350056100 ⚠
tubulin tyrosine ligase, putative
— OG7
LTRL590_160009200 ⚠
tubulin tyrosine ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.